PURPOSE: The purpose of this study was to evaluate the oncologic and functional outcomes of intersphincteric resection in ultralow rectal cancer. METHODS: From 2000 to 2007, intersphincteric resection with total mesorectal excision was performed in 40 patients with very low rectal cancer (total intersphincteric resection in 5 patients, partial intersphincteric resection in 23 patients, and partial intersphincteric resection with partial dentate line preservation [modified partial intersphincteric resection] in 12 patients). The preoperative tumor stage was T12N01M0. RESULTS: Morbidity occurred in three patients (anastomotic leakage in one patient, wound infection in two patients), but there was no postoperative mortality. The five-year overall survival rate was 97 percent, and the five-year disease-free survival rate was 86 percent. Patients who underwent a modified partial intersphincteric resection (P = 0.004) or a partial intersphincteric resection (P = 0.008) had significantly better continence than those who underwent total intersphincteric resection, and patients with a diverting stoma had significantly better continence (P = 0.043) than those without a stoma, at 12 months after surgery. CONCLUSIONS: Intersphincteric resection is a safe procedure for sphincter-saving rectal surgery in selected patients with very low rectal tumors. A temporary diverting stoma may be beneficial to improve anal function. Modified partial intersphincteric resection under the precondition of radical resection yielded better anal function and a lower rate of incontinence.
PURPOSE: The purpose of this study was to evaluate the oncologic and functional outcomes of intersphincteric resection in ultralow rectal cancer. METHODS: From 2000 to 2007, intersphincteric resection with total mesorectal excision was performed in 40 patients with very low rectal cancer (total intersphincteric resection in 5 patients, partial intersphincteric resection in 23 patients, and partial intersphincteric resection with partial dentate line preservation [modified partial intersphincteric resection] in 12 patients). The preoperative tumor stage was T12N01M0. RESULTS: Morbidity occurred in three patients (anastomotic leakage in one patient, wound infection in two patients), but there was no postoperative mortality. The five-year overall survival rate was 97 percent, and the five-year disease-free survival rate was 86 percent. Patients who underwent a modified partial intersphincteric resection (P = 0.004) or a partial intersphincteric resection (P = 0.008) had significantly better continence than those who underwent total intersphincteric resection, and patients with a diverting stoma had significantly better continence (P = 0.043) than those without a stoma, at 12 months after surgery. CONCLUSIONS: Intersphincteric resection is a safe procedure for sphincter-saving rectal surgery in selected patients with very low rectal tumors. A temporary diverting stoma may be beneficial to improve anal function. Modified partial intersphincteric resection under the precondition of radical resection yielded better anal function and a lower rate of incontinence.
Authors: Johannes Klose; Ignazio Tarantino; Yakup Kulu; Thomas Bruckner; Stefan Trefz; Thomas Schmidt; Martin Schneider; Thilo Hackert; Markus W Büchler; Alexis Ulrich Journal: J Gastrointest Surg Date: 2016-12-15 Impact factor: 3.452