Literature DB >> 19502396

Feedback regulation of Lac repressor expression in Escherichia coli.

Stefan Oehler1.   

Abstract

Negative feedback regulation, mediated through repressor binding site O3, which overlaps the lacI gene, could explain the robustness of the weak expression of Lac repressor. Significant autorepression of Lac repressor has never been ruled out. In the work presented here, the degree of autoregulation of Lac repressor was determined. It is negligible.

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Year:  2009        PMID: 19502396      PMCID: PMC2725603          DOI: 10.1128/JB.00427-09

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  17 in total

1.  Is nitrocellulose filter binding really a universal assay for protein-DNA interactions?

Authors:  S Oehler; R Alex; A Barker
Journal:  Anal Biochem       Date:  1999-03-15       Impact factor: 3.365

Review 2.  The lactose operon-controlling elements: a complex paradigm.

Authors:  W S Reznikoff
Journal:  Mol Microbiol       Date:  1992-09       Impact factor: 3.501

3.  Genetic regulatory mechanisms in the synthesis of proteins.

Authors:  F JACOB; J MONOD
Journal:  J Mol Biol       Date:  1961-06       Impact factor: 5.469

Review 4.  Quantitative approaches to the study of bistability in the lac operon of Escherichia coli.

Authors:  Moisés Santillán; Michael C Mackey
Journal:  J R Soc Interface       Date:  2008-08-06       Impact factor: 4.118

5.  Specific destruction of the second lac operator decreases repression of the lac operon in Escherichia coli fivefold.

Authors:  E Eismann; B von Wilcken-Bergmann; B Müller-Hill
Journal:  J Mol Biol       Date:  1987-06-20       Impact factor: 5.469

6.  A perfectly symmetric lac operator binds the lac repressor very tightly.

Authors:  J R Sadler; H Sasmor; J L Betz
Journal:  Proc Natl Acad Sci U S A       Date:  1983-11       Impact factor: 11.205

7.  SsrA-mediated tagging and proteolysis of LacI and its role in the regulation of lac operon.

Authors:  T Abo; T Inada; K Ogawa; H Aiba
Journal:  EMBO J       Date:  2000-07-17       Impact factor: 11.598

8.  Possible ideal lac operator: Escherichia coli lac operator-like sequences from eukaryotic genomes lack the central G X C pair.

Authors:  A Simons; D Tils; B von Wilcken-Bergmann; B Müller-Hill
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

9.  Induction of the lac promoter in the absence of DNA loops and the stoichiometry of induction.

Authors:  Stefan Oehler; Siegfried Alberti; Benno Müller-Hill
Journal:  Nucleic Acids Res       Date:  2006-01-23       Impact factor: 16.971

Review 10.  Dynamics of single-cell gene expression.

Authors:  Diane Longo; Jeff Hasty
Journal:  Mol Syst Biol       Date:  2006-11-28       Impact factor: 11.429

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  5 in total

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Review 2.  Supercoiling biases the formation of loops involved in gene regulation.

Authors:  Laura Finzi; David Dunlap
Journal:  Biophys Rev       Date:  2016-07-05

3.  Cell-Free Protein Synthesis by Diversifying Bacterial Transcription Machinery.

Authors:  Marina Snapyan; Sylvain Robin; Garabet Yeretssian; Michèle Lecocq; Frédéric Marc; Vehary Sakanyan
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4.  Distribution of fitness effects of mutations obtained from a simple genetic regulatory network model.

Authors:  R G Brajesh; Dibyendu Dutta; Supreet Saini
Journal:  Sci Rep       Date:  2019-07-08       Impact factor: 4.379

5.  Metagenomic identification, purification and characterisation of the Bifidobacterium adolescentis BgaC β-galactosidase.

Authors:  Daniel Mehabie Mulualem; Christy Agbavwe; Lesley A Ogilvie; Brian V Jones; Michelle Kilcoyne; Conor O'Byrne; Aoife Boyd
Journal:  Appl Microbiol Biotechnol       Date:  2021-01-11       Impact factor: 4.813

  5 in total

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