Literature DB >> 19500935

Rhabdomyolysis in MDMA intoxication: a rapid and underestimated killer. "Clean" Ecstasy, a safe party drug?

Herve Vanden Eede1, Leon J Montenij, Daan J Touw, Elizabeth M Norris.   

Abstract

BACKGROUND: Ecstasy is a popular drug among young adults. It is often thought to be safe. The dose of methylenedioxymethamphetamine (MDMA) in a tablet of Ecstasy varies greatly, and there is also a difference in individual response to a dose of MDMA.
OBJECTIVES: To increase the awareness of potential mortality in MDMA use. CASE REPORT: We report the case of a patient with a lethal intoxication after pure MDMA intoxication. The serum toxicology screening showed an elevated level of MDMA (1.5 mg/L) but no other amphetamines or other drugs.
CONCLUSIONS: The cause of death was a rapidly evolving hyperkalemia due to rhabdomyolysis. There is still a need to educate the public about the dangers of this so-called "safe" party drug.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2009        PMID: 19500935     DOI: 10.1016/j.jemermed.2009.04.057

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  6 in total

1.  Bilateral pan-plexus lesion after substance use: A case report.

Authors:  Dilek Eker Büyükşireci; Musa Polat; Murat Zinnuroğlu; Bülent Cengiz; Gülçin Kaymak Kaymak Karataş
Journal:  Turk J Phys Med Rehabil       Date:  2019-11-22

Review 2.  Systematic review of nephrotoxicity of drugs of abuse, 2005-2016.

Authors:  Kanaan Mansoor; Murad Kheetan; Saba Shahnawaz; Anna P Shapiro; Eva Patton-Tackett; Larry Dial; Gary Rankin; Prasanna Santhanam; Antonios H Tzamaloukas; Tibor Nadasdy; Joseph I Shapiro; Zeid J Khitan
Journal:  BMC Nephrol       Date:  2017-12-29       Impact factor: 2.388

3.  Comparison of Stimulant-Related Presentations to Victorian Emergency Departments Pre-pandemic and During the COVID-19 Pandemic.

Authors:  Peter T Redona; Cindy Woods; Debra Jackson; Jane Hayman; Kim Usher
Journal:  Cureus       Date:  2022-09-05

4.  Nontraumatic rhabdomyolysis with short-term alcohol intoxication - a case report.

Authors:  Stamatis S Papadatos; Georgios Deligiannis; George Bazoukis; Paschalia Michelongona; Aikaterini Spiliopoulou; Stefanos Mylonas; Christos Zissis
Journal:  Clin Case Rep       Date:  2015-08-20

5.  Ecstasy induces reactive oxygen species, kidney water absorption and rhabdomyolysis in normal rats. Effect of N-acetylcysteine and Allopurinol in oxidative stress and muscle fiber damage.

Authors:  Ana C de Bragança; Regina L M Moreau; Thales de Brito; Maria H M Shimizu; Daniele Canale; Denise A de Jesus; Ana M G Silva; Pedro H Gois; Antonio C Seguro; Antonio J Magaldi
Journal:  PLoS One       Date:  2017-07-05       Impact factor: 3.240

Review 6.  Designer drugs: mechanism of action and adverse effects.

Authors:  Dino Luethi; Matthias E Liechti
Journal:  Arch Toxicol       Date:  2020-04-06       Impact factor: 5.153

  6 in total

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