BACKGROUND: This study explored the relatively neglected role of chronic stress in major depression, examining the independent contributions of co-occurring chronic and acute stress to depression, whether chronic stress predicts acute life events, and whether the two types of stress interact such that greater chronic stress confers greater sensitivity-or resistance-to the depressive effects of acute stressors. METHODS: From a sample of 816 community women, those who had a major depression onset in the past 9 months and those without major depressive episodes (MDE) onset and with no history of current or recent dysthymic disorder were compared on interview-based measures of antecedent acute and chronic stress. Chronic stress interviews rated objective stress in multiple everyday role domains, and acute stress was evaluated with contextual threat interviews. RESULTS: MDE onset was significantly associated with both chronic and acute stress; chronic stress was also associated with the occurrence of acute events, and there was a trend suggesting that increased acute stress is more strongly associated with depression in those with high versus low chronic stress. CONCLUSIONS: Results suggest the importance of including assessment of chronic stress in fully understanding the extent and mechanisms of stress-depression relationships. (c) 2009 Wiley-Liss, Inc.
BACKGROUND: This study explored the relatively neglected role of chronic stress in major depression, examining the independent contributions of co-occurring chronic and acute stress to depression, whether chronic stress predicts acute life events, and whether the two types of stress interact such that greater chronic stress confers greater sensitivity-or resistance-to the depressive effects of acute stressors. METHODS: From a sample of 816 community women, those who had a major depression onset in the past 9 months and those without major depressive episodes (MDE) onset and with no history of current or recent dysthymic disorder were compared on interview-based measures of antecedent acute and chronic stress. Chronic stress interviews rated objective stress in multiple everyday role domains, and acute stress was evaluated with contextual threat interviews. RESULTS:MDE onset was significantly associated with both chronic and acute stress; chronic stress was also associated with the occurrence of acute events, and there was a trend suggesting that increased acute stress is more strongly associated with depression in those with high versus low chronic stress. CONCLUSIONS: Results suggest the importance of including assessment of chronic stress in fully understanding the extent and mechanisms of stress-depression relationships. (c) 2009 Wiley-Liss, Inc.
Authors: Dwight L Evans; Dennis S Charney; Lydia Lewis; Robert N Golden; Jack M Gorman; K Ranga Rama Krishnan; Charles B Nemeroff; J Douglas Bremner; Robert M Carney; James C Coyne; Mahlon R Delong; Nancy Frasure-Smith; Alexander H Glassman; Philip W Gold; Igor Grant; Lisa Gwyther; Gail Ironson; Robert L Johnson; Andres M Kanner; Wayne J Katon; Peter G Kaufmann; Francis J Keefe; Terence Ketter; Thomas P Laughren; Jane Leserman; Constantine G Lyketsos; William M McDonald; Bruce S McEwen; Andrew H Miller; Dominique Musselman; Christopher O'Connor; John M Petitto; Bruce G Pollock; Robert G Robinson; Steven P Roose; Julia Rowland; Yvette Sheline; David S Sheps; Gregory Simon; David Spiegel; Albert Stunkard; Trey Sunderland; Paul Tibbits; William J Valvo Journal: Biol Psychiatry Date: 2005-08-01 Impact factor: 13.382
Authors: L Rojo-Moreno; L Livianos-Aldana; G Cervera-Martínez; J A Dominguez-Carabantes; M J Reig-Cebrian Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2002-12 Impact factor: 4.328
Authors: Cynthia R Davis; Nicole Usher; Eric Dearing; Ayelet R Barkai; Cynthia Crowell-Doom; Shevaun D Neupert; Christos S Mantzoros; Judith A Crowell Journal: Psychosom Med Date: 2014-10 Impact factor: 4.312