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Literature DB >> 19492378

Luminescent terbium protein labels for time-resolved microscopy and screening.

Harsha E Rajapakse¹, D Rajasekhar Reddy, Shabnam Mohandessi, Nathaniel G Butlin, Lawrence W Miller.

Abstract

Brilliance of terbium: Heterodimeric conjugates of trimethoprim covalently linked to sensitized terbium chelates bind to Escherichia coli dihydrofolate reductase fusion proteins with nanomolar affinity (see picture). Terbium luminescence enables sensitive and time-resolved detection of labeled proteins in vitro and on the surface of living mammalian cells.

Entities: CellLine Chemical Disease Species

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Year: 2009 PMID： 19492378 PMCID： PMC3127283 DOI： 10.1002/anie.200900858

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

21 in total

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Journal: Anal Biochem Date: 2004-06-15 Impact factor: 3.365

3. Synthesis and characterisation of highly emissive and kinetically stable lanthanide complexes suitable for usage "in cellulo".

Authors: Robert A Poole; Gabriella Bobba; Martin J Cann; Juan-Carlos Frias; David Parker; Robert D Peacock
Journal: Org Biomol Chem Date: 2005-03-02 Impact factor: 3.876

4. In vivo protein labeling with trimethoprim conjugates: a flexible chemical tag.

Authors: Lawrence W Miller; Yunfei Cai; Michael P Sheetz; Virginia W Cornish
Journal: Nat Methods Date: 2005-04 Impact factor: 28.547

Review 5. Bioconjugation with stable luminescent lanthanide(III) chelates comprising pyridine subunits.

Authors: Jari Hovinen; Pamela M Guy
Journal: Bioconjug Chem Date: 2009-03-18 Impact factor: 4.774

6. Amine-reactive forms of a luminescent diethylenetriaminepentaacetic acid chelate of terbium and europium: attachment to DNA and energy transfer measurements.

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Journal: Bioconjug Chem Date: 1997 Mar-Apr Impact factor: 4.774

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Authors: J Chen; P R Selvin
Journal: Bioconjug Chem Date: 1999 Mar-Apr Impact factor: 4.774

8. Stable lanthanide luminescence agents highly emissive in aqueous solution: multidentate 2-hydroxyisophthalamide complexes of Sm(3+), Eu(3+), Tb(3+), Dy(3+).

Authors: Stéphane Petoud; Seth M Cohen; Jean-Claude G Bünzli; Kenneth N Raymond
Journal: J Am Chem Soc Date: 2003-11-05 Impact factor: 15.419

9. Targeted molecular imaging agents for cellular-scale bimodal imaging.

Authors: H Charles Manning; Timothy Goebel; Reid C Thompson; Ronald R Price; Haakil Lee; Darryl J Bornhop
Journal: Bioconjug Chem Date: 2004 Nov-Dec Impact factor: 4.774

10. Glass beads load macromolecules into living cells.

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Journal: J Cell Sci Date: 1987-12 Impact factor: 5.285

18 in total

1. Time-resolved luminescence resonance energy transfer imaging of protein-protein interactions in living cells.

Authors: Harsha E Rajapakse; Nivriti Gahlaut; Shabnam Mohandessi; Dan Yu; Jerrold R Turner; Lawrence W Miller
Journal: Proc Natl Acad Sci U S A Date: 2010-07-19 Impact factor: 11.205

2. A single sensitizer for the excitation of visible and NIR lanthanide emitters in water with high quantum yields.

Authors: Ga-Lai Law; Tiffany A Pham; Jide Xu; Kenneth N Raymond
Journal: Angew Chem Int Ed Engl Date: 2012-01-24 Impact factor: 15.336

3. Design, synthesis, and application of the trimethoprim-based chemical tag for live-cell imaging.

Authors: Chaoran Jing; Virginia W Cornish
Journal: Curr Protoc Chem Biol Date: 2013

4. Synthesis and luminescent properties of lanthanide complexes with structurally related novel multipodal ligands.

Authors: Qing Wang; Xu-Huan Yan; Wei-Sheng Liu; Min-Yu Tan; Yu Tang
Journal: J Fluoresc Date: 2010-03 Impact factor: 2.217

5. Evaluating the performance of time-gated live-cell microscopy with lanthanide probes.

Authors: Megha Rajendran; Lawrence W Miller
Journal: Biophys J Date: 2015-07-21 Impact factor: 4.033

6. Luminescence resonance energy transfer in the cytoplasm of live Escherichia coli cells.

Authors: Daniel González; Nayanish Lokhande; Swaraj Vadde; Qi Zhao; Aaron Cassill; Robert Renthal
Journal: Biochemistry Date: 2011-07-21 Impact factor: 3.162

7. Cell-penetrating peptides as delivery vehicles for a protein-targeted terbium complex.

Authors: Shabnam Mohandessi; Megha Rajendran; Darren Magda; Lawrence W Miller
Journal: Chemistry Date: 2012-07-17 Impact factor: 5.236

8. Luminescent trimethoprim-polyaminocarboxylate lanthanide complex conjugates for selective protein labeling and time-resolved bioassays.

Authors: D Rajasekhar Reddy; Laura E Pedró Rosa; Lawrence W Miller
Journal: Bioconjug Chem Date: 2011-06-07 Impact factor: 4.774

9. Efficient route to pre-organized and linear polyaminopolycarboxylates: Cy-TTHA, Cy-DTPA and mono/di- reactive, tert-butyl protected TTHA/Cy-TTHA.

Authors: Ali Mohamadi; Lawrence W Miller
Journal: Tetrahedron Lett Date: 2017-02-20 Impact factor: 2.415

10. Brightly Luminescent and Kinetically Inert Lanthanide Bioprobes Based on Linear and Preorganized Chelators.

Authors: Ali Mohamadi; Lawrence W Miller
Journal: Bioconjug Chem Date: 2016-10-03 Impact factor: 4.774