Literature DB >> 19490216

The CTLA4 +49 A/G polymorphism is not associated with susceptibility to type 1 diabetes mellitus in the Portuguese population.

M C Lemos1, E Coutinho, L Gomes, M Bastos, A Fagulha, L Barros, F Carrilho, E Geraldes, F J Regateiro, M Carvalheiro.   

Abstract

CTLA4 genetic polymorphisms have been associated with type 1 diabetes. We genotyped 207 patients and 249 controls for the most frequently investigated polymorphism of the CTLA4 gene (+49A/G (rs231775)). No significant differences were observed, suggesting that this polymorphism is not strongly associated with type 1 diabetes in the Portuguese population.

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Year:  2009        PMID： 19490216     DOI： 10.1111/j.1744-313X.2009.00844.x

Source DB:  PubMed          Journal:  Int J Immunogenet        ISSN： 1744-3121            Impact factor:   1.466


  5 in total

1.  Interaction between CTLA4 gene and IBD5 locus in Hungarian Crohn's disease patients.

Authors:  Veronika Csöngei; Luca Járomi; Eniko Sáfrány; Csilla Sipeky; Lili Magyari; Noémi Polgár; Judit Bene; Patrícia Sarlós; Lilla Lakner; Eszter Baricza; Melinda Szabó; Gábor Rappai; Béla Melegh
Journal:  Int J Colorectal Dis       Date:  2011-04-26       Impact factor: 2.571

2.  Association of single nucleotide polymorphisms in cytotoxic T-lymphocyte antigen 4 and susceptibility to autoimmune type 1 diabetes in Tunisians.

Authors:  Jihen Benmansour; Mouna Stayoussef; Fayza A Al-Jenaidi; Mansoor H Rajab; Chiheb B Rayana; Hichem B Said; Touhami Mahjoub; Wassim Y Almawi
Journal:  Clin Vaccine Immunol       Date:  2010-07-07

3.  Association of Cytotoxic T-Lymphocyte Antigen-4 Gene Polymorphism with Type 1 Diabetes Mellitus: In silico Analysis of Biological Features of CTLA-4 Protein on Ethiopian Population.

Authors:  Endris Ebrahim; Takele Teklu; Fitsumbrhan Tajebe; Tadelo Wondmagegn; Yibeltal Akelew; Mesfin Fiseha
Journal:  Diabetes Metab Syndr Obes       Date:  2022-09-05       Impact factor: 3.249

4.  CTLA-4 (+49A/G) polymorphism and type-1 diabetes in Turkish children.

Authors:  Fatih Çelmeli; Doğa Türkkahraman; Deniz Özel; Sema Akçurin; Olcay Yegin
Journal:  J Clin Res Pediatr Endocrinol       Date:  2013-07-01

5.  Common variants on cytotoxic T lymphocyte antigen-4 polymorphisms contributes to type 1 diabetes susceptibility: evidence based on 58 studies.

Authors:  Jingnan Wang; Lianyong Liu; Junhua Ma; Fei Sun; Zefei Zhao; Mingjun Gu
Journal:  PLoS One       Date:  2014-01-23       Impact factor: 3.240
  5 in total

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