Literature DB >> 19488765

Sacral neuromodulation for the treatment of fecal incontinence and urinary incontinence in female patients: long-term follow-up.

Galal El-Gazzaz1, Massarat Zutshi, Levilester Salcedo, Jeff Hammel, Raymond Rackley, Tracy Hull.   

Abstract

PURPOSE: The purpose of this study was to evaluate improvement in symptoms of fecal incontinence (FI) in a group of women who also had urinary incontinence (UI) and were successfully implanted with the sacral neuromodulation (SNM) device primarily for urinary incontinence in one US institution.
METHODS: Twenty-four patients with FI and UI who failed to improve with conservative or standard surgical treatment underwent permanent SNM after a successful peripheral nerve stimulation test during 2003-2007. Wexner incontinence score, fecal incontinence quality of life (FIQL), and Bristol stool scales were recorded before and after treatment. Follow-up was done by questionnaires contact.
RESULTS: Twenty-four patients (mean age 56.5 +/- 5.3 years) were studied. The median follow-up was 28 months (range 3-49). Twenty-two patients (92%) were contacted. Seven patients (31.8%) experienced improvement in both urinary and fecal incontinence symptoms. Twelve patients (54.5%) experienced no improvement in FI symptoms after SNM. Four patients required a colostomy or ileostomy; four had the system explanted (two, due to a faded clinical response and two, due to infection); and four other patients experienced no improvement after SNM. The outcomes of ten patients (45.5%) with functioning SNM were reviewed. There were significant improvement of FI symptoms with a significantly lower Wexner score from 12.0 +/- 2.0 before SNM to 4.7 +/- 3.6 (p = 0.009). The mean FIQL scores improved significantly from the baseline score 7.8 +/- 0.8 before SNM to 13.5 +/- 2.6 (p = 0.009). Bristol stool form scale was reduced significantly from 4.5 to 3.5 after SNM (p = 0.02).
CONCLUSIONS: SNM may be beneficial in selected female patients with UI associated with FI. Prospective trials may help delineate which patients will show FI improvement in this combined group.

Entities:  

Mesh:

Year:  2009        PMID: 19488765     DOI: 10.1007/s00384-009-0745-8

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  28 in total

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4.  Preliminary results of peripheral transcutaneous neuromodulation in the treatment of idiopathic fecal incontinence.

Authors:  M Queralto; G Portier; P H Cabarrot; G Bonnaud; J P Chotard; M Nadrigny; F Lazorthes
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6.  Sacral neuromodulation in patients with fecal incontinence: a single-center study.

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7.  The functional and psychosocial impact of fecal incontinence on women with urinary incontinence.

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8.  Improvement of bowel dysfunction with sacral neuromodulation for refractory urge urinary incontinence.

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9.  Tools for fecal incontinence assessment: lessons for inflammatory bowel disease trials based on a systematic review.

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