| Literature DB >> 19487447 |
Marco Maria D'Andrea1, Tommaso Giani, Silvia D'Arezzo, Alessandro Capone, Nicola Petrosillo, Paolo Visca, Francesco Luzzaro, Gian Maria Rossolini.
Abstract
Two epidemiologically unrelated carbapenem-resistant Acinetobacter baumannii isolates were investigated as representatives of the first Italian isolates producing the OXA-24 carbapenemase. Both isolates were of European clonal lineage II and carried an identical OXA-24-encoding plasmid, named pABVA01. Comparative analysis revealed that in pABVA01, bla(OXA-24) was part of a DNA module flanked by conserved inverted repeats homologous to XerC/XerD binding sites, which in other Acinetobacter plasmids flank different DNA modules, suggesting mobilization by a novel site-specific recombination mechanism.Entities:
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Year: 2009 PMID: 19487447 PMCID: PMC2715606 DOI: 10.1128/AAC.00178-09
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191