Literature DB >> 19484502

A dramatic case of genital radionecrosis.

José Guzmán-Esquivel1, Ivan Delgado-Enciso, Héctor Solano-Moreno.   

Abstract

BACKGROUND: Epidermoid carcinoma of the penis presents in 1% of malignant tumors in men. Penis cancer treatment has traditionally been total or partial amputation. There are authors who consider radiation to be part of penis cancer treatment in select cases--especially the use of brachytherapy and external radiation. CLINICAL CASE: The case of a 48-year-old male who in 2004 presented with an ulcerated lesion of the penis that was left unattended to is presented. Two years later, he sought medical attention and physical examination revealed an ulcerated penile lesion with poorly defined edges and limited to the glans. DIAGNOSIS: The lesion was biopsied and the histopathological study reported Epidermoid Carcinoma. After radiological studies, it was classified as stage T2-N0-M0. TREATMENT: Total penectomy without lymphadenectomy was performed. The patient received adjuvant treatment of 15 sessions of cobalt radiation treatment at a dose of 3,500 cGy. Six months later, the patient noticed the presence of erythema at the genital and inguinal level which later ulcerated and extended toward the perineum. The disease progressed tragically and the patient died 2 years later.

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Year:  2009        PMID: 19484502     DOI: 10.1007/s11255-009-9591-4

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  21 in total

1.  Laryngeal chondronecrosis: clinical variations and comments on recognition and management.

Authors:  H K Kashima; M J Holliday; V J Hyams
Journal:  Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol       Date:  1977 Sep-Oct

Review 2.  Pulmonary effects of radiation therapy.

Authors:  N J Gross
Journal:  Ann Intern Med       Date:  1977-01       Impact factor: 25.391

Review 3.  Severe radiation injuries of the lung.

Authors:  B Roswit; D C White
Journal:  AJR Am J Roentgenol       Date:  1977-07       Impact factor: 3.959

4.  Radiation fibrosis and necrosis of the larynx.

Authors:  J R Chandler
Journal:  Ann Otol Rhinol Laryngol       Date:  1979 Jul-Aug       Impact factor: 1.547

5.  Reappraisal of the role of radiotherapy and surgery in the management of carcinoma of the penis.

Authors:  M I el-Demiry; R T Oliver; H F Hope-Stone; J P Blandy
Journal:  Br J Urol       Date:  1984-12

Review 6.  Advanced penile carcinoma.

Authors:  Daniel J Culkin; Tomasz M Beer
Journal:  J Urol       Date:  2003-08       Impact factor: 7.450

7.  Squamous cell carcinoma of the penis. III. Treatment of regional lymph nodes.

Authors:  S Horenblas; H van Tinteren; J F Delemarre; L M Moonen; V Lustig; E W van Waardenburg
Journal:  J Urol       Date:  1993-03       Impact factor: 7.450

8.  The results of primary radiation therapy in the management of squamous cell carcinoma of the penis.

Authors:  M McLean; A M Akl; P Warde; R Bissett; T Panzarella; M Gospodarowicz
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-03-15       Impact factor: 7.038

9.  Squamous cell carcinoma of the penis: accuracy of tumor, nodes and metastasis classification system, and role of lymphangiography, computerized tomography scan and fine needle aspiration cytology.

Authors:  S Horenblas; H Van Tinteren; J F Delemarre; L M Moonen; V Lustig; R Kröger
Journal:  J Urol       Date:  1991-11       Impact factor: 7.450

10.  Role of radiation therapy in the treatment of carcinoma of the penis.

Authors:  R Ravi; H K Chaturvedi; D V Sastry
Journal:  Br J Urol       Date:  1994-11
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