Literature DB >> 19481841

Antiviral evaluation of N-amino-1,2,3-triazoles against Cantagalo virus replication in cell culture.

Alessandro K Jordão1, Priscila P Afonso, Vitor F Ferreira, Maria C B V de Souza, Maria C B Almeida, Cristiana O Beltrame, Daniel P Paiva, Solange M S V Wardell, James L Wardell, Edward R T Tiekink, Clarissa R Damaso, Anna C Cunha.   

Abstract

This paper describes the antiviral evaluation of new N-amino-1,2,3-triazole derivatives, 1-(substituted-phenylamino)-5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid ethyl esters, 3 and 1-(4-substituted-phenylamino)-5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid hydrazides, 4, on Cantagalo virus replication. 1-(4-Fluoro-phenylamino)-5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid hydrazide, 4e, exhibited a significant antiviral effect. Characterization of all compounds was confirmed by IR, (1)H and (13)C spectroscopies and elemental analysis. In addition, molecular structure of 4e was also reported.

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Year:  2009        PMID： 19481841     DOI： 10.1016/j.ejmech.2009.04.046

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  7 in total

1.  Parallel synthesis of novel antitumor agents: 1,2,3-triazoles bearing biologically active sulfonamide moiety and their 3D-QSAR.

Authors:  Lili Ou; Shuang Han; Wenbo Ding; Ping Jia; Bo Yang; Jose L Medina-Franco; Marc A Giulianotti; Jian-Zhong Chen; Yongping Yu
Journal:  Mol Divers       Date:  2011-07-10       Impact factor: 2.943

2.  Exploring N-acylhydrazone derivatives against clinical resistant bacterial strains.

Authors:  Andressa C Lannes; Bruno Leal; Juliana S Novais; Viviane Lione; Georgia C T S Monteiro; André L Lourenço; Plínio C Sathler; Alessandro K Jordão; Carlos R Rodrigues; Lúcio M Cabral; Anna Claudia Cunha; Vinicius Campos; Vítor F Ferreira; Maria Cecília B V de Souza; Dilvani O Santos; Helena C Castro
Journal:  Curr Microbiol       Date:  2014-05-08       Impact factor: 2.188

3.  Synthesis and biological evaluation of novel flavone/triazole/benzimidazole hybrids and flavone/isoxazole-annulated heterocycles as antiproliferative and antimycobacterial agents.

Authors:  Yerrabelly Jayaprakash Rao; Thummala Sowjanya; Gogula Thirupathi; Nandula Yadagiri Sreenivasa Murthy; Sudha Sravanti Kotapalli
Journal:  Mol Divers       Date:  2018-06-04       Impact factor: 2.943

4.  [1-(3-Chloro-phen-yl)-1H-1,2,3-triazol-4-yl]methanol hemihydrate.

Authors:  Nübia Boechat; Maria de Lourdes G Ferreira; Monica M Bastos; James L Wardell; Solange M S V Wardell; Edward R T Tiekink
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-10-12

Review 5.  Triazole analogues as potential pharmacological agents: a brief review.

Authors:  Sachin Kumar; Sukhbir Lal Khokra; Akash Yadav
Journal:  Futur J Pharm Sci       Date:  2021-05-25

6.  Antivenom effects of 1,2,3-triazoles against Bothrops jararaca and Lachesis muta snakes.

Authors:  Thaisa F S Domingos; Laura de A Moura; Carla Carvalho; Vinícius R Campos; Alessandro K Jordão; Anna C Cunha; Vitor F Ferreira; Maria Cecília B V de Souza; Eladio F Sanchez; André L Fuly
Journal:  Biomed Res Int       Date:  2013-04-22       Impact factor: 3.411

7.  Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity.

Authors:  Rajiv Kumar; Vikas Sharma; Silvia Bua; Claudiu T Supuran; Pawan K Sharma
Journal:  J Enzyme Inhib Med Chem       Date:  2017-12       Impact factor: 5.051
  7 in total

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