| Literature DB >> 19481450 |
Brian R Lahue1, Yao Ma, Gerald W Shipps, Wolfgang Seghezzi, Ronald Herbst.
Abstract
Substituted benzimidazoles were profiled as inhibitors of kinesin spindle protein (KSP), an increasingly important target for the development of anticancer drugs. This series demonstrated the monoastral phenotypic response and was found to be active in both enzymatic and cellular-based assays.Entities:
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Year: 2009 PMID： 19481450 DOI： 10.1016/j.bmcl.2009.05.040
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823