BACKGROUND: This study aimed to demonstrate how much examination findings and laboratory values can be helpful in the diagnosis of osteomyelitis in patients with diabetic foot infections. MATERIAL/ METHODS: Data of 46 consecutive inpatients prospectively followed up according to a specially designed "Diabetic Foot Follow-up Form" were analyzed. Following diagnostic interventions, clinical and laboratory findings of patients with and without a diagnosis of osteomyelitis were compared. In these patients with and without osteomyelitis confirmed by histopathology and/or microbiology and/or MRI the sensitivity and specificity of ESR (erythrocyte sedimentation rate) and wound size were also determined. RESULTS: There was no significant differences in the duration of diabetes or the existence of nephropathy or vascular disease, while the other findings (ESR, C-reactive protein, wound size, history of diabetic foot ulcer, and retinopathy) were significantly different. It is found that ESR > or =65 mm/h together with a wound size > or =2 cm2 had a sensitivity of 83%, specificity of 77%, positive predictive value of 80%, and negative predictive value of 81% in the diagnosis of osteomyelitis. CONCLUSIONS: This study demonstrated that simple clinical evaluation and laboratory findings without using expensive imaging methods may be important indicators of osteomyelitis.
BACKGROUND: This study aimed to demonstrate how much examination findings and laboratory values can be helpful in the diagnosis of osteomyelitis in patients with diabetic foot infections. MATERIAL/ METHODS: Data of 46 consecutive inpatients prospectively followed up according to a specially designed "Diabetic Foot Follow-up Form" were analyzed. Following diagnostic interventions, clinical and laboratory findings of patients with and without a diagnosis of osteomyelitis were compared. In these patients with and without osteomyelitis confirmed by histopathology and/or microbiology and/or MRI the sensitivity and specificity of ESR (erythrocyte sedimentation rate) and wound size were also determined. RESULTS: There was no significant differences in the duration of diabetes or the existence of nephropathy or vascular disease, while the other findings (ESR, C-reactive protein, wound size, history of diabetic foot ulcer, and retinopathy) were significantly different. It is found that ESR > or =65 mm/h together with a wound size > or =2 cm2 had a sensitivity of 83%, specificity of 77%, positive predictive value of 80%, and negative predictive value of 81% in the diagnosis of osteomyelitis. CONCLUSIONS: This study demonstrated that simple clinical evaluation and laboratory findings without using expensive imaging methods may be important indicators of osteomyelitis.
Authors: B M Ertugrul; O Oncul; N Tulek; A Willke; S Sacar; O G Tunccan; E Yilmaz; O Kaya; B Ozturk; O Turhan; N Yapar; M Ture; F Akin Journal: Eur J Clin Microbiol Infect Dis Date: 2012-02-22 Impact factor: 3.267
Authors: Lawrence A Lavery; Junho Ahn; Easton C Ryan; Kavita Bhavan; Orhan K Oz; Javier La Fontaine; Dane K Wukich Journal: Clin Orthop Relat Res Date: 2019-07 Impact factor: 4.176
Authors: Suzanne Av Van Asten; Adam Nichols; Javier La Fontaine; Kavita Bhavan; Edgar Jg Peters; Lawrence A Lavery Journal: Int Wound J Date: 2015-12-03 Impact factor: 3.315