Literature DB >> 19475634

Evidence for epistasis between SLC6A4 and a chromosome 4 gene as risk factors in major depression.

Chris D Neff1, Victor Abkevich, Jennifer Potter, Robin Riley, Donna Shattuck, David A Katz.   

Abstract

Linkage analysis on Utah pedigrees with strong family histories of major depression including only cases with the SLC6A4 HTTLPR short allele revealed a linkage peak on chromosome 4 (maximum HLOD = 3.5). This evidence suggests epistasis between SLC6A4 and an unknown gene as risk factors for major depression. (c) 2009 Wiley-Liss, Inc.

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Year:  2010        PMID： 19475634     DOI： 10.1002/ajmg.b.30979

Source DB:  PubMed          Journal:  Am J Med Genet B Neuropsychiatr Genet        ISSN： 1552-4841            Impact factor:   3.568


  3 in total

1.  Suggestive evidence on chromosomes 2 and 19 for HTR1A-independent linkage of genes to major depression.

Authors:  Victor Abkevich; Chris D Neff; Jennifer Potter; Robin Riley; Donna Shattuck; David A Katz
Journal:  Neurogenetics       Date:  2009-10-08       Impact factor: 2.660

2.  Assessment of genetic and nongenetic interactions for the prediction of depressive symptomatology: an analysis of the Wisconsin Longitudinal Study using machine learning algorithms.

Authors:  Nicholas S Roetker; C David Page; James A Yonker; Vicky Chang; Carol L Roan; Pamela Herd; Taissa S Hauser; Robert M Hauser; Craig S Atwood
Journal:  Am J Public Health       Date:  2013-08-08       Impact factor: 9.308

3.  Multigene interactions and the prediction of depression in the Wisconsin Longitudinal Study.

Authors:  Nicholas S Roetker; James A Yonker; Chee Lee; Vicky Chang; Jacob J Basson; Carol L Roan; Taissa S Hauser; Robert M Hauser; Craig S Atwood
Journal:  BMJ Open       Date:  2012-07-02       Impact factor: 2.692
  3 in total

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