Literature DB >> 19465534

Construction and characterization of three lactate dehydrogenase-negative Enterococcus faecalis V583 mutants.

Maria Jönsson1, Zhian Saleihan, Ingolf F Nes, Helge Holo.   

Abstract

The roles of the two ldh genes of Enterococcus faecalis were studied using knockout mutants. Deletion of ldh-1 causes a metabolic shift from homolactic fermentation to ethanol, formate, and acetoin production, with a high level of formate production even under aerobic conditions. Ldh-2 plays only a minor role in lactate production.

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Year:  2009        PMID： 19465534      PMCID： PMC2708445          DOI： 10.1128/AEM.00344-09

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  21 in total

1.  Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.

Authors:  I T Paulsen; L Banerjei; G S A Myers; K E Nelson; R Seshadri; T D Read; D E Fouts; J A Eisen; S R Gill; J F Heidelberg; H Tettelin; R J Dodson; L Umayam; L Brinkac; M Beanan; S Daugherty; R T DeBoy; S Durkin; J Kolonay; R Madupu; W Nelson; J Vamathevan; B Tran; J Upton; T Hansen; J Shetty; H Khouri; T Utterback; D Radune; K A Ketchum; B A Dougherty; C M Fraser
Journal:  Science       Date:  2003-03-28       Impact factor: 47.728

2.  Involvement of pyruvate dehydrogenase in product formation in pyruvate-limited anaerobic chemostat cultures of Enterococcus faecalis NCTC 775.

Authors:  J L Snoep; M J Teixeira de Mattos; P W Postma; O M Neijssel
Journal:  Arch Microbiol       Date:  1990       Impact factor: 2.552

3.  The pyruvate formate-lyase system of Streptococcus faecalis. I. Purification and properties of the formate-pyruvate exchange enzyme.

Authors:  D G Lindmark; P Paolella; N P Wood
Journal:  J Biol Chem       Date:  1969-07-10       Impact factor: 5.157

4.  Efficient insertional mutagenesis in lactococci and other gram-positive bacteria.

Authors:  E Maguin; H Prévost; S D Ehrlich; A Gruss
Journal:  J Bacteriol       Date:  1996-02       Impact factor: 3.490

5.  13C nuclear magnetic resonance analysis of glucose and citrate end products in an ldhL-ldhD double-knockout strain of Lactobacillus plantarum.

Authors:  T Ferain; A N Schanck; J Delcour
Journal:  J Bacteriol       Date:  1996-12       Impact factor: 3.490

6.  IS981-mediated adaptive evolution recovers lactate production by ldhB transcription activation in a lactate dehydrogenase-deficient strain of Lactococcus lactis.

Authors:  Roger S Bongers; Marcel H N Hoefnagel; Marjo J C Starrenburg; Marco A J Siemerink; John G A Arends; Jeroen Hugenholtz; Michiel Kleerebezem
Journal:  J Bacteriol       Date:  2003-08       Impact factor: 3.490

7.  Catabolite repression in Enterococcus faecalis.

Authors:  Mary C Rea; Timothy M Cogan
Journal:  Syst Appl Microbiol       Date:  2003-06       Impact factor: 4.022

8.  A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity.

Authors:  Anthony R Richardson; Stephen J Libby; Ferric C Fang
Journal:  Science       Date:  2008-03-21       Impact factor: 47.728

9.  Generation of an electrochemical proton gradient in Streptococcus cremoris by lactate efflux.

Authors:  R Otto; A S Sonnenberg; H Veldkamp; W N Konings
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

10.  CHEMICALLY DEFINED MEDIUM FOR GROWTH STREPTOCOCCUS PYOGENES.

Authors:  M N MICKELSON
Journal:  J Bacteriol       Date:  1964-07       Impact factor: 3.490
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  15 in total

1.  Growth rate-dependent control in Enterococcus faecalis: effects on the transcriptome and proteome, and strong regulation of lactate dehydrogenase.

Authors:  Ibrahim Mehmeti; Ellen M Faergestad; Martijn Bekker; Lars Snipen; Ingolf F Nes; Helge Holo
Journal:  Appl Environ Microbiol       Date:  2011-10-28       Impact factor: 4.792

2.  Characterization of three lactic acid bacteria and their isogenic ldh deletion mutants shows optimization for YATP (cell mass produced per mole of ATP) at their physiological pHs.

Authors:  Tomas Fiedler; Martijn Bekker; Maria Jonsson; Ibrahim Mehmeti; Anja Pritzschke; Nikolai Siemens; Ingolf Nes; Jeroen Hugenholtz; Bernd Kreikemeyer
Journal:  Appl Environ Microbiol       Date:  2010-11-19       Impact factor: 4.792

3.  Pyruvate formate-lyase is essential for fumarate-independent anaerobic glycerol utilization in the Enterococcus faecalis strain W11.

Authors:  Yuki Doi; Yuki Ikegami
Journal:  J Bacteriol       Date:  2014-04-25       Impact factor: 3.490

4.  Functional genetic analysis of the GarML gene cluster in Lactococcus garvieae DCC43 gives new insights into circular bacteriocin biosynthesis.

Authors:  Christina Gabrielsen; Dag A Brede; Zhian Salehian; Ingolf F Nes; Dzung B Diep
Journal:  J Bacteriol       Date:  2013-12-13       Impact factor: 3.490

5.  Transcriptome, proteome, and metabolite analyses of a lactate dehydrogenase-negative mutant of Enterococcus faecalis V583.

Authors:  Ibrahim Mehmeti; Maria Jönsson; Ellen M Fergestad; Geir Mathiesen; Ingolf F Nes; Helge Holo
Journal:  Appl Environ Microbiol       Date:  2011-02-04       Impact factor: 4.792

6.  High yields of 2,3-butanediol and mannitol in Lactococcus lactis through engineering of NAD⁺ cofactor recycling.

Authors:  Paula Gaspar; Ana Rute Neves; Michael J Gasson; Claire A Shearman; Helena Santos
Journal:  Appl Environ Microbiol       Date:  2011-08-12       Impact factor: 4.792

7.  Enterococcus faecalis Antagonizes Pseudomonas aeruginosa Growth in Mixed-Species Interactions.

Authors:  Casandra Ai Zhu Tan; Ling Ning Lam; Goran Biukovic; Eliza Ye-Chen Soh; Xiao Wei Toh; José A Lemos; Kimberly A Kline
Journal:  J Bacteriol       Date:  2022-06-27       Impact factor: 3.476

8.  Class IIa bacteriocin resistance in Enterococcus faecalis V583: the mannose PTS operon mediates global transcriptional responses.

Authors:  Mona Opsata; Ingolf F Nes; Helge Holo
Journal:  BMC Microbiol       Date:  2010-08-25       Impact factor: 3.605

9.  Redox balance via lactate dehydrogenase is important for multiple stress resistance and virulence in Enterococcus faecalis.

Authors:  Nosheen Fatima Rana; Nicolas Sauvageot; Jean-Marie Laplace; Yinyin Bao; Ingolf Nes; Alain Rincé; Brunella Posteraro; Maurizio Sanguinetti; Axel Hartke
Journal:  Infect Immun       Date:  2013-05-06       Impact factor: 3.441

10.  Regulation of the activity of lactate dehydrogenases from four lactic acid bacteria.

Authors:  Anna Feldman-Salit; Silvio Hering; Hanan L Messiha; Nadine Veith; Vlad Cojocaru; Antje Sieg; Hans V Westerhoff; Bernd Kreikemeyer; Rebecca C Wade; Tomas Fiedler
Journal:  J Biol Chem       Date:  2013-05-17       Impact factor: 5.157
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