Literature DB >> 19464002

Is factor V Leiden mutation a cause of in vitro fertilization failure?

Briana Rudick1, H Irene Su, Mary D Sammel, George Kovalevsky, Alka Shaunik, Kurt Barnhart.   

Abstract

This prospective cohort study tested whether the most common hereditary thrombophilia, factor V Leiden (FVL) mutation, is associated with nonpregnancy after IVF. Factor V Leiden mutation prevalence was very low (1.6%) and had a preliminarily positive association with pregnancy, suggesting that routine testing in a general IVF population for FVL mutation as a cause of IVF failure and infertility is not indicated.

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Year:  2009        PMID: 19464002     DOI: 10.1016/j.fertnstert.2009.03.089

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  3 in total

1.  Multiple thrombophilic single nucleotide polymorphisms lack a significant effect on outcomes in fresh IVF cycles: an analysis of 1717 patients.

Authors:  George Patounakis; Eric Bergh; Eric J Forman; Xin Tao; Agnieszka Lonczak; Jason M Franasiak; Nathan Treff; Richard T Scott
Journal:  J Assist Reprod Genet       Date:  2015-11-06       Impact factor: 3.412

2.  Reduced protein C Global assay level in infertile women prior to IVF-ET treatment.

Authors:  Johnny S Younis; Moshe Ben-Ami; Ido Izhaki; Benjamin Brenner; Galit Sarig
Journal:  J Assist Reprod Genet       Date:  2013-11-06       Impact factor: 3.412

3.  Association between in vitro fertilization outcomes and inherited thrombophilias: a meta-analysis.

Authors:  Xiaofang Tan; Zhenbo Yu; Jun Sao; Li Chen; Ya Shen; Jiayi Ding; Weihong Shi
Journal:  J Assist Reprod Genet       Date:  2016-05-23       Impact factor: 3.412

  3 in total

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