Literature DB >> 19460528

Pretransplant model for end-stage liver disease score as a predictor of postoperative complications after liver transplantation.

A Siniscalchi1, A Cucchetti, L Toccaceli, R Spiritoso, E Tommasoni, S Spedicato, A Dante, L Riganello, A Zanoni, M Cimatti, E Pierucci, E Bernardi, Z Miklosova, A D Pinna, S Faenza.   

Abstract

The model for end-stage liver disease (MELD) is used to determine organ allocation priorities for orthotopic liver transplantation (OLT), although its value to predict posttransplantation mortality and morbility is controversial. The aim of this study was to analyze postoperative courses and (to evaluate the relationships between MELD score and postoperative) complications. We retrospectively examined the courses of 242 patients including 186 males and 56 females of overall mean age of 53 +/- 10 years who underwent primary liver transplantation. The classification of Dindo-characterized 5 grades of severity to evaluate postoperative events. The data showed that 171 patients (70.7%) experienced complications, while 71 (29.3%) had none. We observed that MELD score and complications were related (P < .05). Patients with complicated courses post-OLT displayed a 22.80 mean value of the MELD score, while those without complications showed a 17.64 mean value. The MELD score was also significantly associated with the time of intensive care unit stay and in hospital. Finally, we noted that MELD score and mortality were significantly correlated (P < .05). In conclusion, MELD score can be considered to be an objective system to predict the prevalence and severity of postoperative complications after liver transplantation.

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Year:  2009        PMID: 19460528     DOI: 10.1016/j.transproceed.2009.02.046

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  5 in total

1.  Ventilator associated pneumonia following liver transplantation: Etiology, risk factors and outcome.

Authors:  Antonio Siniscalchi; Lucia Aurini; Beatrice Benini; Lorenzo Gamberini; Stefano Nava; Pierluigi Viale; Stefano Faenza
Journal:  World J Transplant       Date:  2016-06-24

2.  Association of HLA-DPA1 polymorphism with prolonged mechanical ventilation in patients undergoing liver transplantation.

Authors:  Eun Jung Kim; Min-Soo Kim; Myoung Soo Kim; Junhyun Nam; Seung Ho Choi
Journal:  Korean J Anesthesiol       Date:  2022-05-03

3.  Aorto-hepatic bypass in liver transplantation in the MELD-era: outcomes after supraceliac and infrarenal bypasses.

Authors:  Richard Hummel; Sabrina Irmscher; Christina Schleicher; Norbert Senninger; Jens G Brockmann; Heiner H Wolters
Journal:  Surg Today       Date:  2013-03-05       Impact factor: 2.549

4.  Model of end stage liver disease (MELD) score greater than 23 predicts length of stay in the ICU but not mortality in liver transplant recipients.

Authors:  Christian E Oberkofler; Philipp Dutkowski; Reto Stocker; Reto A Schuepbach; John F Stover; Pierre-Alain Clavien; Markus Béchir
Journal:  Crit Care       Date:  2010-06-15       Impact factor: 9.097

5.  Comparison of Different Scoring Systems Based on Both Donor and Recipient Characteristics for Predicting Outcome after Living Donor Liver Transplantation.

Authors:  Yucheng Ma; Qing Wang; Jiayin Yang; Lunan Yan
Journal:  PLoS One       Date:  2015-09-17       Impact factor: 3.240

  5 in total

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