Literature DB >> 19459537

The ghost in our genes: legal and ethical implications of epigenetics.

Mark A Rothstein1, Yu Cai, Gary E Marchant.   

Abstract

Epigenetics is one of the most scientifically important, and legally and ethically significant, cutting-edge subjects of scientific discovery. Epigenetics link environmental and genetic influences on the traits and characteristics of an individual, and new discoveries reveal that a large range of environmental, dietary, behavioral, and medical experiences can significantly affect the future development and health of an individual and their offspring. This article describes and analyzes the ethical and legal implications of these new scientific findings.

Entities:  

Mesh：

Year:  2009        PMID： 19459537      PMCID： PMC3034450     

Source DB:  PubMed          Journal:  Health Matrix Clevel        ISSN： 0748-383X


  115 in total

Review 1.  The history of cancer epigenetics.

Authors:  Andrew P Feinberg; Benjamin Tycko
Journal:  Nat Rev Cancer       Date:  2004-02       Impact factor: 60.716

2.  Epigenetics and twins: three variations on the theme.

Authors:  Arturas Petronis
Journal:  Trends Genet       Date:  2006-05-11       Impact factor: 11.639

Review 3.  Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond.

Authors:  Catherine Gallou-Kabani; Alexandre Vigé; Marie-Sylvie Gross; Claudine Junien
Journal:  Clin Chem Lab Med       Date:  2007       Impact factor: 3.694

Review 4.  Epigenetic decisions in mammalian germ cells.

Authors:  Christopher B Schaefer; Steen K T Ooi; Timothy H Bestor; Déborah Bourc'his
Journal:  Science       Date:  2007-04-20       Impact factor: 47.728

Review 5.  Phenotypic plasticity and the epigenetics of human disease.

Authors:  Andrew P Feinberg
Journal:  Nature       Date:  2007-05-24       Impact factor: 49.962

6.  Maternal and grandmaternal smoking patterns are associated with early childhood asthma.

Authors:  Yu-Fen Li; Bryan Langholz; Muhammad T Salam; Frank D Gilliland
Journal:  Chest       Date:  2005-04       Impact factor: 9.410

Review 7.  Epigenetics and the environment.

Authors:  Jessica E Sutherland; Max Costa
Journal:  Ann N Y Acad Sci       Date:  2003-03       Impact factor: 5.691

Review 8.  CpG islands: their potential as biomarkers for cancer.

Authors:  Huidong Shi; Michael X Wang; Charles W Caldwell
Journal:  Expert Rev Mol Diagn       Date:  2007-09       Impact factor: 5.225

Review 9.  An epigenetic approach to cancer etiology.

Authors:  Andrew P Feinberg
Journal:  Cancer J       Date:  2007 Jan-Feb       Impact factor: 3.360

10.  Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome.

Authors:  Dana C Dolinoy; Jennifer R Weidman; Robert A Waterland; Randy L Jirtle
Journal:  Environ Health Perspect       Date:  2006-04       Impact factor: 9.031
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  23 in total

1.  The myth of genetic enhancement.

Authors:  Philip M Rosoff
Journal:  Theor Med Bioeth       Date:  2012-06

Review 2.  Developmental Origins, Epigenetics, and Equity: Moving Upstream.

Authors:  Lawrence Wallack; Kent Thornburg
Journal:  Matern Child Health J       Date:  2016-05

Review 3.  Epigenome-based cancer risk prediction: rationale, opportunities and challenges.

Authors:  Martin Widschwendter; Allison Jones; Iona Evans; Daniel Reisel; Joakim Dillner; Karin Sundström; Ewout W Steyerberg; Yvonne Vergouwe; Odette Wegwarth; Felix G Rebitschek; Uwe Siebert; Gaby Sroczynski; Inez D de Beaufort; Ineke Bolt; David Cibula; Michal Zikan; Line Bjørge; Nicoletta Colombo; Nadia Harbeck; Frank Dudbridge; Anne-Marie Tasse; Bartha M Knoppers; Yann Joly; Andrew E Teschendorff; Nora Pashayan
Journal:  Nat Rev Clin Oncol       Date:  2018-02-27       Impact factor: 66.675

4.  Epigenetics and primary care.

Authors:  David B Lehane; Vincent T Cunliffe; Caroline Mitchell; Chris Burton
Journal:  Br J Gen Pract       Date:  2018-01       Impact factor: 5.386

5.  Ethical implications of epigenetics research.

Authors:  Mark A Rothstein; Yu Cai; Gary E Marchant
Journal:  Nat Rev Genet       Date:  2009-04       Impact factor: 53.242

Review 6.  A community survey on knowledge of the impact of environmental and epigenetic factors on health and disease.

Authors:  Marian Miller; Banita Bailey; Vinothini Govindarajah; Linda Levin; Traci Metzger; Susan M Pinney; Yuet-Kin Leung; Shuk-Mei Ho
Journal:  Perspect Public Health       Date:  2016-03-03

Review 7.  Transgenerational and intergenerational epigenetic inheritance in allergic diseases.

Authors:  Toril Mørkve Knudsen; Faisal I Rezwan; Yu Jiang; Wilfried Karmaus; Cecilie Svanes; John W Holloway
Journal:  J Allergy Clin Immunol       Date:  2018-07-21       Impact factor: 10.793

8.  Epigenome data release: a participant-centered approach to privacy protection.

Authors:  Stephanie O M Dyke; Warren A Cheung; Yann Joly; Ole Ammerpohl; Pavlo Lutsik; Mark A Rothstein; Maxime Caron; Stephan Busche; Guillaume Bourque; Lars Rönnblom; Paul Flicek; Stephan Beck; Martin Hirst; Henk Stunnenberg; Reiner Siebert; Jörn Walter; Tomi Pastinen
Journal:  Genome Biol       Date:  2015-07-17       Impact factor: 13.583

9.  The social brain meets the reactive genome: neuroscience, epigenetics and the new social biology.

Authors:  Maurizio Meloni
Journal:  Front Hum Neurosci       Date:  2014-05-21       Impact factor: 3.169

10.  Social Epigenetics and Equality of Opportunity.

Authors:  Michele Loi; Lorenzo Del Savio; Elia Stupka
Journal:  Public Health Ethics       Date:  2013-07-15       Impact factor: 1.940
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