Literature DB >> 22528149

The myth of genetic enhancement.

Philip M Rosoff1.   

Abstract

The ongoing revolution in molecular genetics has led many to speculate that one day we will be able to change the expression or phenotype of numerous complex traits to improve ourselves in many different ways. The prospect of genetic enhancements has generated heated controversy, with proponents advocating research and implementation, with caution advised for concerns about justice, and critics tending to see the prospect of genetic enhancements as an assault on human freedom and human nature. Both camps base their arguments on the unquestioned assumption that the science will realize either their dreams or nightmares. In this paper, I show that their beliefs are based upon two fundamental mistakes. First, they are based upon an unwarranted reliance in a genetic determinism that takes for granted that the traits that we might most want to enhance, like intelligence, aggression, shyness, and even athletic ability, can be causally directed by specific genes. In so doing, character descriptions are reified to be concrete and discrete entities, in this case, genes. Second, they have accepted on faith that there is, or will be, a science to translate their hopes or worries into reality when, in fact, that is unlikely to occur because of the irreducible complexity of phenotypic expression.

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Year:  2012        PMID: 22528149     DOI: 10.1007/s11017-012-9220-6

Source DB:  PubMed          Journal:  Theor Med Bioeth        ISSN: 1386-7415


  62 in total

1.  Are "genetic enhancements" really enhancements?

Authors:  D Shickle
Journal:  Camb Q Healthc Ethics       Date:  2000       Impact factor: 1.284

2.  Ageless bodies, happy souls: biotechnology and the pursuit of perfection.

Authors:  Leon R Kass
Journal:  New Atlantis       Date:  2003

3.  Epigenetic transgenerational actions of endocrine disruptors and male fertility.

Authors:  Matthew D Anway; Andrea S Cupp; Mehmet Uzumcu; Michael K Skinner
Journal:  Science       Date:  2005-06-03       Impact factor: 47.728

4.  Epigenetic influences may explain dental differences in monozygotic twin pairs.

Authors:  G C Townsend; L Richards; T Hughes; S Pinkerton; W Schwerdt
Journal:  Aust Dent J       Date:  2005-06       Impact factor: 2.291

5.  Epigenetics and twins: three variations on the theme.

Authors:  Arturas Petronis
Journal:  Trends Genet       Date:  2006-05-11       Impact factor: 11.639

Review 6.  Justice, fairness, and enhancement.

Authors:  Julian Savulescu
Journal:  Ann N Y Acad Sci       Date:  2006-12       Impact factor: 5.691

7.  Aesthetics and ethics: the implications of cosmetic surgery.

Authors:  D A Hyman
Journal:  Perspect Biol Med       Date:  1990       Impact factor: 1.416

8.  Better than men? Sex and the therapy/enhancement distinction.

Authors:  Robert Sparrow
Journal:  Kennedy Inst Ethics J       Date:  2010-06

9.  New breeds of humans: the moral obligation to enhance.

Authors:  Julian Savulescu
Journal:  Reprod Biomed Online       Date:  2005-03       Impact factor: 3.828

10.  Dynamical systems theory in physiology.

Authors:  Arthur Sherman
Journal:  J Gen Physiol       Date:  2011-07       Impact factor: 4.086

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  4 in total

1.  Challenges of using next generation sequencing in newborn screening.

Authors:  Eyal Reinstein
Journal:  Genet Res (Camb)       Date:  2015-11-02       Impact factor: 1.588

2.  On the anthropological foundation of bioethics: a critique of the work of J.-F. Malherbe.

Authors:  Henri Mbulu
Journal:  Theor Med Bioeth       Date:  2013-10

3.  Enhancement and Civic Virtue.

Authors:  Will Jefferson; Thomas Douglas; Guy Kahane; Julian Savulescu
Journal:  Soc Theory Pract       Date:  2014-07

Review 4.  Limits to human enhancement: nature, disease, therapy or betterment?

Authors:  Bjørn Hofmann
Journal:  BMC Med Ethics       Date:  2017-10-10       Impact factor: 2.652

  4 in total

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