Literature DB >> 19458405

Toward a wide-field retinal prosthesis.

Hossein Ameri1, Tanapat Ratanapakorn, Stefan Ufer, Helmut Eckhardt, Mark S Humayun, James D Weiland.   

Abstract

The purpose of this paper is to present a wide field electrode array that may increase the field of vision in patients implanted with a retinal prosthesis. Mobility is often impaired in patients with low vision, particularly in those with peripheral visual loss. Studies on low vision patients as well as simulation studies on normally sighted individuals have indicated a strong correlation between the visual field and mobility. In addition, it has been shown that an increased visual field is associated with a significant improvement in visual acuity and object discrimination. Current electrode arrays implanted in animals or human vary in size; however, the retinal area covered by the electrodes has a maximum projected visual field of about 10 degrees. We have designed wide field electrode arrays that could potentially provide a visual field of 34 degrees, which may significantly improve the mobility. Tests performed on a mechanical eye model showed that it was possible to fix 10 mm wide flexible polyimide dummy electrode arrays onto the retina using a single retinal tack. They also showed that the arrays could conform to the inner curvature of the eye. Surgeries on an enucleated porcine eye model demonstrated feasibility of implantation of 10 mm wide arrays through a 5 mm eye wall incision.

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Mesh:

Year:  2009        PMID: 19458405      PMCID: PMC2861858          DOI: 10.1088/1741-2560/6/3/035002

Source DB:  PubMed          Journal:  J Neural Eng        ISSN: 1741-2552            Impact factor:   5.379


  44 in total

1.  Pattern electrical stimulation of the human retina.

Authors:  M S Humayun; E de Juan; J D Weiland; G Dagnelie; S Katona; R Greenberg; S Suzuki
Journal:  Vision Res       Date:  1999-07       Impact factor: 1.886

2.  Management of glass intraocular foreign bodies.

Authors:  L Gopal; A S Banker; N Deb; S S Badrinath; T Sharma; S N Parikh; M P Shanmugham; P S Bhende; D Das; B N Mukesh
Journal:  Retina       Date:  1998       Impact factor: 4.256

3.  Traditional measures of mobility performance and retinitis pigmentosa.

Authors:  D R Geruschat; K A Turano; J W Stahl
Journal:  Optom Vis Sci       Date:  1998-07       Impact factor: 1.973

4.  Mobility of people with retinitis pigmentosa as a function of vision and psychological variables.

Authors:  S Haymes; D Guest; A Heyes; A Johnston
Journal:  Optom Vis Sci       Date:  1996-10       Impact factor: 1.973

5.  Subretinal semiconductor microphotodiode array.

Authors:  G Peyman; A Y Chow; C Liang; V Y Chow; J I Perlman; N S Peachey
Journal:  Ophthalmic Surg Lasers       Date:  1998-03

6.  Preservation of the inner retina in retinitis pigmentosa. A morphometric analysis.

Authors:  A Santos; M S Humayun; E de Juan; R J Greenburg; M J Marsh; I B Klock; A H Milam
Journal:  Arch Ophthalmol       Date:  1997-04

7.  Long-term histological and electrophysiological results of an inactive epiretinal electrode array implantation in dogs.

Authors:  A B Majji; M S Humayun; J D Weiland; S Suzuki; S A D'Anna; E de Juan
Journal:  Invest Ophthalmol Vis Sci       Date:  1999-08       Impact factor: 4.799

8.  Associations between specific measures of vision and vision-related quality of life in patients with bothnia dystrophy, a defined type of retinitis pigmentosa.

Authors:  Marie S I Burstedt; Eva Mönestam; Ola Sandgren
Journal:  Retina       Date:  2005 Apr-May       Impact factor: 4.256

9.  Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa.

Authors:  M S Humayun; M Prince; E de Juan; Y Barron; M Moskowitz; I B Klock; A H Milam
Journal:  Invest Ophthalmol Vis Sci       Date:  1999-01       Impact factor: 4.799

10.  Visual perception elicited by electrical stimulation of retina in blind humans.

Authors:  M S Humayun; E de Juan; G Dagnelie; R J Greenberg; R H Propst; D H Phillips
Journal:  Arch Ophthalmol       Date:  1996-01
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  8 in total

1.  Task-dependent V1 responses in human retinitis pigmentosa.

Authors:  Yoichiro Masuda; Hiroshi Horiguchi; Serge O Dumoulin; Ayumu Furuta; Satoru Miyauchi; Satoshi Nakadomari; Brian A Wandell
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-05-05       Impact factor: 4.799

Review 2.  Retinal prosthesis.

Authors:  James D Weiland; Mark S Humayun
Journal:  IEEE Trans Biomed Eng       Date:  2014-04-02       Impact factor: 4.538

3.  Development of very large electrode arrays for epiretinal stimulation (VLARS).

Authors:  Florian Waschkowski; Stephan Hesse; Anne Christine Rieck; Tibor Lohmann; Claudia Brockmann; Thomas Laube; Norbert Bornfeld; Gabriele Thumann; Peter Walter; Wilfried Mokwa; Sandra Johnen; Gernot Roessler
Journal:  Biomed Eng Online       Date:  2014-02-06       Impact factor: 2.819

4.  Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesis.

Authors:  Laura Ferlauto; Marta Jole Ildelfonsa Airaghi Leccardi; Naïg Aurelia Ludmilla Chenais; Samuel Charles Antoine Gilliéron; Paola Vagni; Michele Bevilacqua; Thomas J Wolfensberger; Kevin Sivula; Diego Ghezzi
Journal:  Nat Commun       Date:  2018-03-08       Impact factor: 14.919

5.  Implantation of multiple suprachoroidal electrode arrays in rabbits.

Authors:  Walid Abdallah; Wen Li; James Weiland; Mark Humayun; Hossein Ameri
Journal:  J Curr Ophthalmol       Date:  2017-12-09

6.  Testing of Newly Developed Wide-Field Dual-Array Suprachoroidal-Transretinal Stimulation Prosthesis in Dogs.

Authors:  Takeshi Morimoto; Takashi Fujikado; Hiroyuki Kanda; Tomomitsu Miyoshi; Takao Endo; Kentaro Nishida; Haruhiko Kishima; Toru Saito; Kunihiko Ito; Motoki Ozawa; Kohji Nishida
Journal:  Transl Vis Sci Technol       Date:  2021-03-01       Impact factor: 3.283

Review 7.  Retinal prostheses: progress toward the next generation implants.

Authors:  Diego Ghezzi
Journal:  Front Neurosci       Date:  2015-08-20       Impact factor: 4.677

8.  Shape Morphable Hydrogel/Elastomer Bilayer for Implanted Retinal Electronics.

Authors:  Muru Zhou; Do Hyun Kang; Jinsang Kim; James D Weiland
Journal:  Micromachines (Basel)       Date:  2020-04-09       Impact factor: 2.891

  8 in total

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