Literature DB >> 19450524

Of elections and cell-death decisions.

Paul Loriaux1, Alexander Hoffmann.   

Abstract

A new study in the journal Nature (Spencer et al., 2009) argues that cell-to-cell variation in the decision to undergo apoptosis is not due to genetic, epigenetic, or cell-cycle differences, nor due to random molecular noise, but instead is determined by differences in protein abundances.

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Year:  2009        PMID： 19450524      PMCID： PMC3703440          DOI： 10.1016/j.molcel.2009.05.001

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  9 in total

1.  Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis.

Authors:  Kathryn Miller-Jensen; Kevin A Janes; Yun-Ling Wong; Linda G Griffith; Douglas A Lauffenburger
Journal:  J Cell Sci       Date:  2006-08-29       Impact factor: 5.285

Review 2.  Noise in gene expression: origins, consequences, and control.

Authors:  Jonathan M Raser; Erin K O'Shea
Journal:  Science       Date:  2005-09-23       Impact factor: 47.728

3.  Variability and memory of protein levels in human cells.

Authors:  Alex Sigal; Ron Milo; Ariel Cohen; Naama Geva-Zatorsky; Yael Klein; Yuvalal Liron; Nitzan Rosenfeld; Tamar Danon; Natalie Perzov; Uri Alon
Journal:  Nature       Date:  2006-11-19       Impact factor: 49.962

Review 4.  Timescales of genetic and epigenetic inheritance.

Authors:  Oliver J Rando; Kevin J Verstrepen
Journal:  Cell       Date:  2007-02-23       Impact factor: 41.582

5.  UV as an amplifier rather than inducer of NF-kappaB activity.

Authors:  Ellen L O'Dea; Jeffrey D Kearns; Alexander Hoffmann
Journal:  Mol Cell       Date:  2008-06-06       Impact factor: 17.970

6.  Quantitative analysis of pathways controlling extrinsic apoptosis in single cells.

Authors:  John G Albeck; John M Burke; Bree B Aldridge; Mingsheng Zhang; Douglas A Lauffenburger; Peter K Sorger
Journal:  Mol Cell       Date:  2008-04-11       Impact factor: 17.970

7.  Dynamics of outer mitochondrial membrane permeabilization during apoptosis.

Authors:  M Rehm; H J Huber; C T Hellwig; S Anguissola; H Dussmann; J H M Prehn
Journal:  Cell Death Differ       Date:  2009-01-09       Impact factor: 15.828

8.  Adjuvant chemotherapy.

Authors:  H E Skipper
Journal:  Cancer       Date:  1978-03       Impact factor: 6.860

9.  Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.

Authors:  Sabrina L Spencer; Suzanne Gaudet; John G Albeck; John M Burke; Peter K Sorger
Journal:  Nature       Date:  2009-04-12       Impact factor: 49.962
  9 in total
  2 in total

1.  MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer.

Authors:  Yoshimi Endo Greer; Samuel F Gilbert; Brunilde Gril; Rajesh Narwal; Danielle L Peacock Brooks; David A Tice; Patricia S Steeg; Stanley Lipkowitz
Journal:  Breast Cancer Res       Date:  2019-02-18       Impact factor: 6.466

2.  An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions.

Authors:  Marie Oliver Metzig; Ying Tang; Simon Mitchell; Brooks Taylor; Robert Foreman; Roy Wollman; Alexander Hoffmann
Journal:  Mol Syst Biol       Date:  2020-12       Impact factor: 11.429
  2 in total

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