Literature DB >> 1944824

Therapeutic effect of sodium dichloroacetate on visual and auditory hallucinations in a patient with MELAS.

T Saijo1, E Naito, M Ito, E Takeda, T Hashimoto, Y Kuroda.   

Abstract

We report a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes who experienced visual and auditory hallucinations. His blood and cerebrospinal fluid lactate levels were remarkably elevated. Sodium dichloroacetate was administered orally at doses of 12.5 to 100 mg/kg/day. On normalization of the lactate levels, the hallucinations disappeared.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1944824     DOI： 10.1055/s-2008-1071436

Source DB:  PubMed          Journal:  Neuropediatrics        ISSN： 0174-304X            Impact factor:   1.947


  6 in total

1.  Treatment of congenital lactic acidosis with dichloroacetate.

Authors:  P W Stacpoole; C L Barnes; M D Hurbanis; S L Cannon; D S Kerr
Journal:  Arch Dis Child       Date:  1997-12       Impact factor: 3.791

2.  Metabolic interventions against complex I deficiency in MELAS syndrome.

Authors:  K Majamaa; H Rusanen; A Remes; I E Hassinen
Journal:  Mol Cell Biochem       Date:  1997-09       Impact factor: 3.396

Review 3.  The treatment of congenital lactic acidoses.

Authors:  A A Morris; J V Leonard
Journal:  J Inherit Metab Dis       Date:  1996       Impact factor: 4.982

4.  Beneficial effect of sodium dichloroacetate in muscle cytochrome C oxidase deficiency.

Authors:  A B Burlina; O Milanesi; P Biban; A Bordugo; B Garavaglia; F Zacchello; S DiMauro
Journal:  Eur J Pediatr       Date:  1993-06       Impact factor: 3.183

Review 5.  Physiology and pathophysiology of organic acids in cerebrospinal fluid.

Authors:  G F Hoffmann; W Meier-Augenstein; S Stöckler; R Surtees; D Rating; W L Nyhan
Journal:  J Inherit Metab Dis       Date:  1993       Impact factor: 4.982

6.  Multiple neurologic, psychiatric, and endocrine complaints in a young woman: a case discussion and review of the clinical features and management of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke.

Authors:  Chaya G Bhuvaneswar; Jared L Goetz; Theodore A Stern
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2008
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.