| Literature DB >> 19447146 |
Adria K Martig1, Graham L Jones, Kelsey E Smith, Sheri J Y Mizumori.
Abstract
Rats were tested on a hippocampus dependent win-shift working memory task in familiar or novel environments after receiving bilateral ventral tegmental area infusions of baclofen. Baclofen infusion disrupted working memory performance in both familiar and novel environments. In addition, baclofen infusion selectively disrupted short-term working memory in the novel environment. This experiment confirms selective ventral tegmental area support of accurate performance during a context dependent spatial navigation task.Entities:
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Year: 2009 PMID: 19447146 PMCID: PMC2709700 DOI: 10.1016/j.bbr.2009.05.008
Source DB: PubMed Journal: Behav Brain Res ISSN: 0166-4328 Impact factor: 3.332