Literature DB >> 19445792

Low back pain (acute).

Hamilton Hall1, Greg McIntosh.   

Abstract

INTRODUCTION: Low back pain (LBP) affects about 70% of people in resource-rich countries at some point. Acute low back pain is usually perceived as self-limiting; however, one year later, as many as 33% of people still have moderate-intensity pain and 15% have severe pain. It has a high recurrence rate; 75% of those with a first episode have a recurrence. Although acute episodes may resolve completely, they may also increase in severity and duration over time. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of oral drug treatments for low back pain? What are the effects of local injections for low back pain? What are the effects of non-drug treatments for low back pain? We searched: Medline, Embase, The Cochrane Library, and other important databases up to May 2007 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS: We found 34 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupuncture, advice to stay active, analgesics (paracetamol, opioids), back exercises, back schools, bed rest, behavioural therapy, electromyographic biofeedback, epidural corticosteroid injections, lumbar supports, massage, multidisciplinary treatment programmes, muscle relaxants, non-steroidal anti-inflammatory drugs (NSAIDs), spinal manipulation (in the short term), temperature treatments (short wave diathermy, ultrasound, ice, heat), traction, and transcutaneous electrical nerve stimulation (TENS).

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Year:  2008        PMID: 19445792      PMCID: PMC2907975     

Source DB:  PubMed          Journal:  BMJ Clin Evid        ISSN: 1462-3846


  38 in total

1.  Multidisciplinary rehabilitation for subacute low back pain: graded activity or workplace intervention or both? A randomized controlled trial.

Authors:  Johannes R Anema; Ivan A Steenstra; Paulien M Bongers; Henrica C W de Vet; Dirk L Knol; Patrick Loisel; Willem van Mechelen
Journal:  Spine (Phila Pa 1976)       Date:  2007-02-01       Impact factor: 3.468

2.  Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen.

Authors:  T Pohjolainen; A Jekunen; L Autio; H Vuorela
Journal:  Spine (Phila Pa 1976)       Date:  2000-06-15       Impact factor: 3.468

3.  [Therapy of acute lumbovertebral syndromes through optimal muscle relaxation using diazepam. Results of a double-blind study on 68 cases].

Authors:  W Moll
Journal:  Med Welt       Date:  1973-11-09

4.  Does early intervention with a light mobilization program reduce long-term sick leave for low back pain?

Authors:  E M Hagen; H R Eriksen; H Ursin
Journal:  Spine (Phila Pa 1976)       Date:  2000-08-01       Impact factor: 3.468

5.  Efficacy and tolerability of paracetamol/tramadol (325 mg/37.5 mg) combination treatment compared with tramadol (50 mg) monotherapy in patients with subacute low back pain: a multicenter, randomized, double-blind, parallel-group, 10-day treatment study.

Authors:  Serge Perrot; Dirk Krause; Philippe Crozes; Claude Naïm
Journal:  Clin Ther       Date:  2006-10       Impact factor: 3.393

6.  Valdecoxib is as efficacious as diclofenac in the treatment of acute low back pain.

Authors:  Antonio Ximenes; Manuel Robles; George Sands; Raul Vinueza
Journal:  Clin J Pain       Date:  2007 Mar-Apr       Impact factor: 3.442

7.  Analgesic efficacy and safety of lornoxicam quick-release formulation compared with diclofenac potassium: randomised, double-blind trial in acute low back pain.

Authors:  N Yakhno; A Guekht; A Skoromets; N Spirin; E Strachunskaya; A Ternavsky; K J Olsen; P L Moller
Journal:  Clin Drug Investig       Date:  2006       Impact factor: 2.859

8.  A randomized clinical trial comparing chiropractic adjustments to muscle relaxants for subacute low back pain.

Authors:  Kathryn T Hoiriis; Bruce Pfleger; Frederic C McDuffie; George Cotsonis; Omar Elsangak; Roger Hinson; Gregoria T Verzosa
Journal:  J Manipulative Physiol Ther       Date:  2004 Jul-Aug       Impact factor: 1.437

9.  Does early intervention with a light mobilization program reduce long-term sick leave for low back pain: a 3-year follow-up study.

Authors:  Eli Molde Hagen; Astrid Grasdal; Hege R Eriksen
Journal:  Spine (Phila Pa 1976)       Date:  2003-10-15       Impact factor: 3.468

10.  A new skeletal muscle relaxant (DS 103-282) compared to diazepam in the treatment of muscle spasm of local origin.

Authors:  O L Hennies
Journal:  J Int Med Res       Date:  1981       Impact factor: 1.671

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