Literature DB >> 1944386

In vivo loss of telomeric repeats with age in humans.

J Lindsey1, N I McGill, L A Lindsey, D K Green, H J Cooke.   

Abstract

Telomeric DNA in the skin cells of 21 human subjects aged between 0 and 92 years was quantified by determining the length of the telomeric smear and the relative amount of TTAGGG repeat sequences. Both telomere length and quantity of telomeric repeat sequences were found to decrease significantly with age. Telomere loss has previously been postulated to be a caused of cell senescence.

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Year:  1991        PMID： 1944386     DOI： 10.1016/0921-8734(91)90032-7

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  112 in total

1.  Functional requirement of p23 and Hsp90 in telomerase complexes.

Authors:  S E Holt; D L Aisner; J Baur; V M Tesmer; M Dy; M Ouellette; J B Trager; G B Morin; D O Toft; J W Shay; W E Wright; M A White
Journal:  Genes Dev       Date:  1999-04-01       Impact factor: 11.361

2.  Activation of p53 protein by telomeric (TTAGGG)n repeats.

Authors:  M Milyavsky; A Mimran; S Senderovich; I Zurer; N Erez; I Shats; N Goldfinger; I Cohen; V Rotter
Journal:  Nucleic Acids Res       Date:  2001-12-15       Impact factor: 16.971

3.  Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells.

Authors:  K Perrem; L M Colgin; A A Neumann; T R Yeager; R R Reddel
Journal:  Mol Cell Biol       Date:  2001-06       Impact factor: 4.272

Review 4.  How long should telomeres be?

Authors:  A Aviv; C B Harley
Journal:  Curr Hypertens Rep       Date:  2001-04       Impact factor: 5.369

5.  Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells.

Authors:  A Satyanarayana; S U Wiemann; J Buer; J Lauber; K E J Dittmar; T Wüstefeld; M A Blasco; M P Manns; K L Rudolph
Journal:  EMBO J       Date:  2003-08-01       Impact factor: 11.598

6.  Asynchronous replication timing of telomeres at opposite arms of mammalian chromosomes.

Authors:  Ying Zou; Sergei M Gryaznov; Jerry W Shay; Woodring E Wright; Michael N Cornforth
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-20       Impact factor: 11.205

7.  Do US Black Women Experience Stress-Related Accelerated Biological Aging?: A Novel Theory and First Population-Based Test of Black-White Differences in Telomere Length.

Authors:  Arline T Geronimus; Margaret T Hicken; Jay A Pearson; Sarah J Seashols; Kelly L Brown; Tracey Dawson Cruz
Journal:  Hum Nat       Date:  2010-03-10

8.  Telomere length and replicative aging in human vascular tissues.

Authors:  E Chang; C B Harley
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

9.  Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres.

Authors:  Neil R Lloyd; Thayne H Dickey; Robert A Hom; Deborah S Wuttke
Journal:  Biochemistry       Date:  2016-09-15       Impact factor: 3.162

Review 10.  Human telomerase and its regulation.

Authors:  Yu-Sheng Cong; Woodring E Wright; Jerry W Shay
Journal:  Microbiol Mol Biol Rev       Date:  2002-09       Impact factor: 11.056
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