Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Fatal case of deer tick virus encephalitis.

Literature DB >> 19439744

Fatal case of deer tick virus encephalitis.

Norma P Tavakoli¹, Heng Wang, Michelle Dupuis, Rene Hull, Gregory D Ebel, Emily J Gilmore, Phyllis L Faust.

Abstract

Deer tick virus is related to Powassan virus, a tickborne encephalitis virus. A 62-year-old man presented with a meningoencephalitis syndrome and eventually died. Analyses of tissue samples obtained during surgery and at autopsy revealed a widespread necrotizing meningoencephalitis. Nucleic acid was extracted from formalin-fixed tissue, and the presence of deer tick virus was verified on a flavivirus-specific polymerase-chain-reaction (PCR) assay, followed by sequence confirmation. Immunohistochemical analysis with antisera specific for deer tick virus identified numerous immunoreactive neurons, with prominent involvement of large neurons in the brain stem, cerebellum, basal ganglia, thalamus, and spinal cord. This case demonstrates that deer tick virus can be a cause of fatal encephalitis. 2009 Massachusetts Medical Society

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Antibodies, Viral

Year: 2009 PMID： 19439744 PMCID： PMC2847876 DOI： 10.1056/NEJMoa0806326

Source DB: PubMed Journal: N Engl J Med ISSN： 0028-4793 Impact factor: 91.245

25 in total

Review 1. Coinfecting deer-associated zoonoses: Lyme disease, babesiosis, and ehrlichiosis.

Authors: C Thompson; A Spielman; P J Krause
Journal: Clin Infect Dis Date: 2001-08-06 Impact factor: 9.079

2. Enzootic transmission of deer tick virus in New England and Wisconsin sites.

Authors: G D Ebel; E N Campbell; H K Goethert; A Spielman; S R Telford
Journal: Am J Trop Med Hyg Date: 2000 Jul-Aug Impact factor: 2.345

3. Powassan virus: isolation of virus from a fatal case of encephalitis.

Authors: D M McLEAN; W L DONOHUE
Journal: Can Med Assoc J Date: 1959-05-01 Impact factor: 8.262

4. Powassan virus meningoencephalitis: a case report.

Authors: M S Wilson; B A Wherrett; M S Mahdy
Journal: Can Med Assoc J Date: 1979-08-04 Impact factor: 8.262

5. Inflammatory response in human tick-borne encephalitis: analysis of postmortem brain tissue.

Authors: Ellen Gelpi; Matthias Preusser; Ute Laggner; Ferenc Garzuly; Heidemarie Holzmann; Franz Xaver Heinz; Herbert Budka
Journal: J Neurovirol Date: 2006-08 Impact factor: 2.643

6. Genomic sequencing of deer tick virus and phylogeny of powassan-related viruses of North America.

Authors: G Kuno; H Artsob; N Karabatsos; K R Tsuchiya; G J Chang
Journal: Am J Trop Med Hyg Date: 2001-11 Impact factor: 2.345

7. The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Authors: N Saitou; M Nei
Journal: Mol Biol Evol Date: 1987-07 Impact factor: 16.240

8. Powassan virus encephalitis resembling herpes simplex encephalitis.

Authors: J A Embil; P Camfield; H Artsob; D P Chase
Journal: Arch Intern Med Date: 1983-02

Review 9. Tick-borne flaviviruses.

Authors: T S Gritsun; P A Nuttall; Ernest A Gould
Journal: Adv Virus Res Date: 2003 Impact factor: 9.937

10. A focus of deer tick virus transmission in the northcentral United States.

Authors: G D Ebel; I Foppa; A Spielman; S R Telford
Journal: Emerg Infect Dis Date: 1999 Jul-Aug Impact factor: 6.883

39 in total

1. The prevalence of zoonotic tick-borne pathogens in Ixodes scapularis collected in the Hudson Valley, New York State.

Authors: Matthew T Aliota; Alan P Dupuis; Michael P Wilczek; Ryan J Peters; Richard S Ostfeld; Laura D Kramer
Journal: Vector Borne Zoonotic Dis Date: 2014-04-01 Impact factor: 2.133

Review 2. Lyme Neuroborreliosis: Clinical Outcomes, Controversy, Pathogenesis, and Polymicrobial Infections.

Authors: Juan Carlos Garcia-Monco; Jorge L Benach
Journal: Ann Neurol Date: 2019-01 Impact factor: 10.422

3. Seroprevalence of Powassan virus in New England deer, 1979-2010.

Authors: Robert A Nofchissey; Eleanor R Deardorff; Tia M Blevins; Michael Anishchenko; Angela Bosco-Lauth; Erica Berl; Charles Lubelczyk; John-Paul Mutebi; Aaron C Brault; Gregory D Ebel; Louis A Magnarelli
Journal: Am J Trop Med Hyg Date: 2013-04-08 Impact factor: 2.345

4. Homogeneity of Powassan virus populations in naturally infected Ixodes scapularis.

Authors: Doug E Brackney; Ivy K Brown; Robert A Nofchissey; Kelly A Fitzpatrick; Gregory D Ebel
Journal: Virology Date: 2010-07-05 Impact factor: 3.616

Review 5. Lyme borreliosis.

Authors: Allen C Steere; Franc Strle; Gary P Wormser; Linden T Hu; John A Branda; Joppe W R Hovius; Xin Li; Paul S Mead
Journal: Nat Rev Dis Primers Date: 2016-12-15 Impact factor: 52.329

6. Prevalence and genetic characterization of Powassan virus strains infecting Ixodes scapularis in Connecticut.

Authors: John F Anderson; Philip M Armstrong
Journal: Am J Trop Med Hyg Date: 2012-08-13 Impact factor: 2.345

Review 7. Tick-Borne Flaviviruses, with a Focus on Powassan Virus.

Authors: Gábor Kemenesi; Krisztián Bányai
Journal: Clin Microbiol Rev Date: 2018-12-12 Impact factor: 26.132

8. Fatal Powassan Encephalitis (Deer Tick Virus, Lineage II) in a Patient With Fever and Orchitis Receiving Rituximab.

Authors: Isaac H Solomon; Kristyn M Spera; Sophia L Ryan; Jeffrey Helgager; Juliana Andrici; Sherif R Zaki; Henrikas Vaitkevicius; Kristoffer E Leon; Michael R Wilson; Joseph L DeRisi; Sophia Koo; Stelios M Smirnakis; Umberto De Girolami
Journal: JAMA Neurol Date: 2018-06-01 Impact factor: 18.302

Review 9. Diagnostic Approach for Arboviral Infections in the United States.

Authors: Anne Piantadosi; Sanjat Kanjilal
Journal: J Clin Microbiol Date: 2020-11-18 Impact factor: 5.948

10. Persistence of pathogens with short infectious periods in seasonal tick populations: the relative importance of three transmission routes.

Authors: Etsuko Nonaka; Gregory D Ebel; Helen J Wearing
Journal: PLoS One Date: 2010-07-23 Impact factor: 3.240