Literature DB >> 1943712

Secretion of a potential virulence factor, a fungal ribonucleotoxin, during human aspergillosis infections.

B Lamy1, M Moutaouakil, J P Latge, J Davies.   

Abstract

We show by cloning and nucleotide sequence analysis that the 18kDa antigen found in the urine of patients suffering from aspergillosis is related to the fungal protein toxins restrictocin and mitogillin. These are inhibitors of translation which act by catalytic inactivation of eukaryotic ribosomes; they may be implicated in the pathogenesis of the disease.

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Year:  1991        PMID: 1943712     DOI: 10.1111/j.1365-2958.1991.tb01930.x

Source DB:  PubMed          Journal:  Mol Microbiol        ISSN: 0950-382X            Impact factor:   3.501


  20 in total

1.  Use of recombinant mitogillin for improved serodiagnosis of Aspergillus fumigatus-associated diseases.

Authors:  M Weig; M Frosch; K Tintelnot; A Haas; U Gross; B Linsmeier; J Heesemann
Journal:  J Clin Microbiol       Date:  2001-05       Impact factor: 5.948

2.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-11-25       Impact factor: 16.971

3.  Biochemical characterization of an immunodominant allergen/antigen ofAspergillus fumigatus.

Authors:  N Bir; A Paliwal; K Muralidhar; P U Sarma
Journal:  Indian J Clin Biochem       Date:  1999-07

4.  An extracellular S1-type nuclease of marine fungus Penicillium melinii.

Authors:  Larissa A Balabanova; Yury M Gafurov; Mikhael V Pivkin; Natalya A Terentyeva; Galina N Likhatskaya; Valery A Rasskazov
Journal:  Mar Biotechnol (NY)       Date:  2011-06-07       Impact factor: 3.619

Review 5.  Virulence factors of medically important fungi.

Authors:  L H Hogan; B S Klein; S M Levitz
Journal:  Clin Microbiol Rev       Date:  1996-10       Impact factor: 26.132

6.  Dipeptidyl-peptidase IV secreted by Aspergillus fumigatus, a fungus pathogenic to humans.

Authors:  A Beauvais; M Monod; J Wyniger; J P Debeaupuis; E Grouzmann; N Brakch; J Svab; A G Hovanessian; J P Latgé
Journal:  Infect Immun       Date:  1997-08       Impact factor: 3.441

7.  Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis.

Authors:  J M Smith; C M Tang; S Van Noorden; D W Holden
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

8.  Detection of gene-disruption events in Aspergillus transformants by polymerase chain reaction direct from conidiospores.

Authors:  A Aufauvre-Brown; C M Tang; D W Holden
Journal:  Curr Genet       Date:  1993 Jul-Aug       Impact factor: 3.886

9.  Expression and characterization of Asp fI, an immunodominant allergen/antigen of A. fumigatus in insect cell.

Authors:  Priyanka Priyadarsiny; Prabodha K Swain; P Usha Sarma
Journal:  Mol Cell Biochem       Date:  2003-10       Impact factor: 3.396

10.  The alkaline protease of Aspergillus fumigatus is not a virulence determinant in two murine models of invasive pulmonary aspergillosis.

Authors:  C M Tang; J Cohen; T Krausz; S Van Noorden; D W Holden
Journal:  Infect Immun       Date:  1993-05       Impact factor: 3.441

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