Literature DB >> 19430726

Capacity of photodynamic therapy for microbial reduction in periodontal pockets.

Sérgio Luiz Pinheiro1, Juliana Marla Donegá, Lia Maura Soares Seabra, Marina Dalto Adabo, Talita Lopes, Thiago Henrique Dias do Carmo, Mariângela Cagnoni Ribeiro, Patrícia Fernanda Roesler Bertolini.   

Abstract

Practitioners are not successful in implemented treatments due to the great difficulty in completely removing bacterial deposits and their endotoxins. This study aimed to evaluate the capacity of photodynamic therapy to reduce the numbers of viable bacteria in periodontal pockets. Microbiological samples were collected before and after scaling and after photodynamic therapy. Photodynamic therapy was performed through the insertion of the photosensitizer toluidine blue and Endo PTC into the pocket for 3 min, followed by photosensitization with low-intensity diode of 4 J/cm(2). The results (log(10)) were submitted to a descriptive analysis and a t-test. A reduction of 81.24% in the numbers of bacteria after scaling was observed, as well as 95.90% after photodynamic therapy (P < 0.01). Photodynamic therapy is indicated as an adjuvant treatment to reduce the numbers of viable bacteria in periodontal diseases.

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Year:  2009        PMID: 19430726     DOI: 10.1007/s10103-009-0671-6

Source DB:  PubMed          Journal:  Lasers Med Sci        ISSN: 0268-8921            Impact factor:   3.161


  19 in total

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Authors:  Akira Aoki; Katia Miyuki Sasaki; Hisashi Watanabe; Isao Ishikawa
Journal:  Periodontol 2000       Date:  2004       Impact factor: 7.589

2.  Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model.

Authors:  Bernd W Sigusch; Anne Pfitzner; Volker Albrecht; Eike Glockmann
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3.  Bactericidal effects of different laser wavelengths on periodontopathic germs in photodynamic therapy.

Authors:  You Chan; Chern-Hsiung Lai
Journal:  Lasers Med Sci       Date:  2003       Impact factor: 3.161

4.  Evaluation of a micromethod for determination of Streptococcus mutans and Lactobacillus infection.

Authors:  G Westergren; B Krasse
Journal:  J Clin Microbiol       Date:  1978-01       Impact factor: 5.948

5.  Subgingival and tongue microbiota during early periodontitis.

Authors:  A C R Tanner; B J Paster; S C Lu; E Kanasi; R Kent; T Van Dyke; S T Sonis
Journal:  J Dent Res       Date:  2006-04       Impact factor: 6.116

6.  In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model.

Authors:  N Kömerik; H Nakanishi; A J MacRobert; B Henderson; P Speight; M Wilson
Journal:  Antimicrob Agents Chemother       Date:  2003-03       Impact factor: 5.191

7.  Sensitization of periodontopathogenic bacteria to killing by light from a low-power laser.

Authors:  M Wilson; J Dobson; S Sarkar
Journal:  Oral Microbiol Immunol       Date:  1993-06

8.  Photoinactivation of bacteria. Use of a cationic water-soluble zinc phthalocyanine to photoinactivate both gram-negative and gram-positive bacteria.

Authors:  A Minnock; D I Vernon; J Schofield; J Griffiths; J H Parish; S T Brown
Journal:  J Photochem Photobiol B       Date:  1996-02       Impact factor: 6.252

9.  Lethal photosensitisation of oral bacteria and its potential application in the photodynamic therapy of oral infections.

Authors:  Michael Wilson
Journal:  Photochem Photobiol Sci       Date:  2004-02-05       Impact factor: 3.982

10.  Comparison of toluidine blue-mediated photodynamic therapy and conventional scaling treatment for periodontitis in rats.

Authors:  Y L Qin; X L Luan; L J Bi; Y Q Sheng; C N Zhou; Z G Zhang
Journal:  J Periodontal Res       Date:  2008-04       Impact factor: 4.419

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  11 in total

Review 1.  Photodynamic therapy in the treatment of chronic periodontitis: a systematic review and meta-analysis.

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Journal:  Lasers Med Sci       Date:  2011-10-16       Impact factor: 3.161

2.  Low-level diode laser therapy reduces lipopolysaccharide (LPS)-induced bone cell inflammation.

Authors:  Tsui Hsien Huang; Yu Chuan Lu; Chia Tze Kao
Journal:  Lasers Med Sci       Date:  2011-10-16       Impact factor: 3.161

3.  Inactivation of Aggregatibacter actinomycetemcomitans by two different modalities of photodynamic therapy using Toluidine blue O or Radachlorin as photosensitizers: an in vitro study.

Authors:  Neda Moslemi; Pardis Soleiman-Zadeh Azar; Abbas Bahador; Nina Rouzmeh; Nasim Chiniforush; Mojgan Paknejad; Reza Fekrazad
Journal:  Lasers Med Sci       Date:  2014-07-01       Impact factor: 3.161

4.  Effect of Antimicrobial Photodynamic Therapy as an Adjunct to Nonsurgical Treatment of Deep Periodontal Pockets: A Clinical Study.

Authors:  Abdul Ahad; Arundeep Kaur Lamba; Farrukh Faraz; Shruti Tandon; Kirti Chawla; Neha Yadav
Journal:  J Lasers Med Sci       Date:  2016-10-27

5.  The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial.

Authors:  Gisele N Campos; Suzana P Pimentel; Fernanda V Ribeiro; Renato C V Casarin; Fabiano R Cirano; Cintia H C Saraceni; Márcio Z Casati
Journal:  Lasers Med Sci       Date:  2012-07-20       Impact factor: 3.161

6.  Increase in the nitric oxide release without changes in cell viability of macrophages after laser therapy with 660 and 808 nm lasers.

Authors:  Igor Henrique Morais Silva; Samantha Cardoso de Andrade; Andreza Barkokebas Santos de Faria; Deborah Daniela Diniz Fonsêca; Luiz Alcino Monteiro Gueiros; Alessandra Albuquerque Tavares Carvalho; Wylla Tatiana Ferreira da Silva; Raul Manhães de Castro; Jair Carneiro Leão
Journal:  Lasers Med Sci       Date:  2016-09-16       Impact factor: 3.161

7.  Additional effects of aPDT on nonsurgical periodontal treatment with doxycycline in type II diabetes: a randomized, controlled clinical trial.

Authors:  Guilherme de Oliveira Macedo; Arthur B Novaes; Sérgio L S Souza; Mário Taba; Daniela B Palioto; Márcio F M Grisi
Journal:  Lasers Med Sci       Date:  2013-03-10       Impact factor: 3.161

8.  An In Vitro Comparison of Antimicrobial Effects of Curcumin-Based Photodynamic Therapy and Chlorhexidine, on Aggregatibacter actinomycetemcomitans.

Authors:  Shamsoulmolouk Najafi; Mina Khayamzadeh; Mojgan Paknejad; Golfam Poursepanj; Mohammad Javad Kharazi Fard; Abbas Bahador
Journal:  J Lasers Med Sci       Date:  2016-01-07

9.  Removal of black stains from teeth by photodynamic therapy: clinical and microbiological analysis.

Authors:  Larissa Pessoa; Virgilio Galvão; Carla Damante; Adriana Campos Passanezi Sant'Ana
Journal:  BMJ Case Rep       Date:  2015-12-23

10.  Curcumin photodynamic effect in the treatment of the induced periodontitis in rats.

Authors:  Letícia Helena Theodoro; Marcio Luiz Ferro-Alves; Mariéllen Longo; Marta Aparecida Alberton Nuernberg; Renata Pironato Ferreira; Adriele Andreati; Edilson Ervolino; Cristiane Duque; Valdir Gouveia Garcia
Journal:  Lasers Med Sci       Date:  2017-07-03       Impact factor: 3.161

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