Benjamin M Greenberg1. 1. Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA. bgreenb7@jhmi.edu
Abstract
BACKGROUND: Often patients with systemic lupus erythematosus (SLE) suffer from neurologic symptoms and at times the diagnosis of SLE is made after patients present with neurologic events. Although diagnostic criteria for SLE have included seizures and psychosis, there are 19 recognized neurologic manifestations of the disease. REVIEW SUMMARY: The various neurologic manifestations of SLE are reviewed as are the various treatment options. The pathophysiology of the major syndromes is reviewed. CONCLUSION: Neurologists need to be familiar with the various ways SLE can present and the various neurologic complications known lupus patients can experience. Because of the various treatment options available, rapid recognition of these syndromes is critical.
BACKGROUND: Often patients with systemic lupus erythematosus (SLE) suffer from neurologic symptoms and at times the diagnosis of SLE is made after patients present with neurologic events. Although diagnostic criteria for SLE have included seizures and psychosis, there are 19 recognized neurologic manifestations of the disease. REVIEW SUMMARY: The various neurologic manifestations of SLE are reviewed as are the various treatment options. The pathophysiology of the major syndromes is reviewed. CONCLUSION: Neurologists need to be familiar with the various ways SLE can present and the various neurologic complications known lupuspatients can experience. Because of the various treatment options available, rapid recognition of these syndromes is critical.
Authors: Simon J Otter; Maheswaran Rohan; Kevin A Davies; Sunil Kumar; Peter Gow; Nicola Dalbeth; Michael Corkill; Sam Panthakalam; Keith Rome Journal: J Foot Ankle Res Date: 2017-07-26 Impact factor: 2.303
Authors: Maria Teresa De Angelis; Gianluca Santamaria; Elvira Immacolata Parrotta; Stefania Scalise; Michela Lo Conte; Sara Gasparini; Edoardo Ferlazzo; Umberto Aguglia; Clara Ciampi; Antonella Sgura; Giovanni Cuda Journal: J Cell Mol Med Date: 2019-09-19 Impact factor: 5.310