| Literature DB >> 19429463 |
Maria Grazia Ursino1, Valentina Vasina, Emanuel Raschi, Francesca Crema, Fabrizio De Ponti.
Abstract
beta(3)-Adrenoceptors (beta(3)-ARs) are located not only on the plasma membrane of both white and brown adipocytes, but also exist in human heart, gall bladder, gastrointestinal tract, prostate, urinary bladder detrusor, brain and in near-term myometrium. They are now recognized as an attractive target for drug discovery and several efforts have been made in this field to understand their function and regulation in different human tissues. The aim of this review is to highlight the functional role of beta(3)-ARs as well as to discuss their potential for drug development.Entities:
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Year: 2009 PMID： 19429463 DOI： 10.1016/j.phrs.2009.01.002
Source DB: PubMed Journal: Pharmacol Res ISSN： 1043-6618 Impact factor: 7.658