Literature DB >> 19427794

The study of physics and thermal characteristics for in-hospital neutron irradiator (IHNI).

Guotu Ke1, Ziyong Sun, Feng Shen, Tiancai Liu, Yiguo Li, Yongmao Zhou.   

Abstract

The IHNI is designed for boron neutron capture therapy (BNCT) based on miniature neutron source reactor (MNSR). The reactor with thermal power 30 kW is an undermoderated reactor of pool-tank type, and UO(2) as fuel, light water as coolant and moderator, and metallic beryllium as reflector. The fission heat produced by the reactor is removed by the natural convection. The paper gives the calculating results of critical mass and the worths of central control rod, auxiliary control rod, reactivity regulator and neutron beam equipments. The parameters at thermal and small thermal ports and at epithermal port were calculated by optimizing combination of kinds of material by MCNP code. The dynamic feature research was done by RELAP5 code when the reactivities of 3, 4.5 and 6 mK were inserted, respectively. The results show that the reactor power can be limited to safe level by itself owing to the Doppler effect of fuel element and moderator negative temperature effect when the 6 mK reactivity was inserted into the reactor.

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Year:  2009        PMID: 19427794     DOI: 10.1016/j.apradiso.2009.03.117

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  4 in total

Review 1.  Boron Neutron Capture Therapy: Current Status and Challenges.

Authors:  Song Wang; Zhengchao Zhang; Lele Miao; Yumin Li
Journal:  Front Oncol       Date:  2022-03-31       Impact factor: 6.244

2.  Boron neutron capture therapy for malignant melanoma: first clinical case report in China.

Authors:  Zhong Yong; Zewen Song; Yongmao Zhou; Tong Liu; Zizhu Zhang; Yanzhong Zhao; Yang Chen; Congjun Jin; Xiang Chen; Jianyun Lu; Rui Han; Pengzhou Li; Xulong Sun; Guohui Wang; Guangqing Shi; Shaihong Zhu
Journal:  Chin J Cancer Res       Date:  2016-12       Impact factor: 5.087

3.  Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals.

Authors:  Guangru Li; Wei Jiang; Lu Zhang; Weiqiang Chen; Qiang Li
Journal:  Front Public Health       Date:  2021-03-11

4.  Boron neutron capture therapy induces cell cycle arrest and cell apoptosis of glioma stem/progenitor cells in vitro.

Authors:  Ting Sun; Zizhu Zhang; Bin Li; Guilin Chen; Xueshun Xie; Yongxin Wei; Jie Wu; Youxin Zhou; Ziwei Du
Journal:  Radiat Oncol       Date:  2013-08-06       Impact factor: 3.481

  4 in total

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