Literature DB >> 19427560

Volumetric modulated arc radiotherapy for vestibular schwannomas.

Frank J Lagerwaard1, Otto W M Meijer, Elles A P van der Hoorn, Wilko F A R Verbakel, Ben J Slotman, Suresh Senan.   

Abstract

PURPOSE: To evaluate volumetric modulated arc radiotherapy (RapidArc [RA]), a novel approach allowing for rapid treatment delivery, for the treatment of vestibular schwannoma (VS). METHODS AND MATERIALS: The RA plans were generated for a small (0.5 cm(3)), intermediate (2.8 cm(3)), and large (14.8 cm(3)) VS. The prescription dose was 12.5 Gy to the encompassing 80% isodose. The RA plans were compared with conventional radiosurgery plans using both a single dynamic conformal arc (1DCA) and five noncoplanar dynamic conformal arcs (5DCA). Conformity indices (CI) and dose-volume histograms of critical organs were compared. The RA plan for the medium-sized VS was measured in a phantom using Gafchromic EBT films and compared with calculated dose distributions.
RESULTS: The RA planning was completed within 30 min in all cases, and calculated treatment delivery time (after patient setup) was 5 min vs. 20 min for 5DCA. A superior CI was achieved with RA, with a substantial decrease in low-dose irradiation of the normal brain achieved relative to 5DCA plans. Maximum doses to critical organs were similar for RA and 5DCA but were higher for 1DCA. Film measurements showed the differences between calculated and measured doses to be smaller than 1.5% in the high-dose area and smaller than 3% in the low-dose area.
CONCLUSION: The RA plans consistently achieved a higher CI and decrease in areas of low-dose irradiation. This, together with shorter treatment delivery times, has led to RA replacing our conventional five-arc radiosurgery technique for VS.

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Year:  2009        PMID: 19427560     DOI: 10.1016/j.ijrobp.2008.12.076

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  33 in total

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Review 2.  Volumetric modulated arc therapy: a review of current literature and clinical use in practice.

Authors:  M Teoh; C H Clark; K Wood; S Whitaker; A Nisbet
Journal:  Br J Radiol       Date:  2011-11       Impact factor: 3.039

3.  Influence of metallic dental implants and metal artefacts on dose calculation accuracy.

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5.  Investigation of two linear accelerator head designs for treating brain metastases with hypofractionated volumetric-modulated arc radiotherapy.

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6.  Neo-adjuvant chemo-radiation of rectal cancer with volumetric modulated arc therapy: summary of technical and dosimetric features and early clinical experience.

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Journal:  Radiat Oncol       Date:  2010-02-19       Impact factor: 3.481

7.  Application of volumetric modulated arc therapy (VMAT) in a dual-vendor environment.

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Journal:  Radiat Oncol       Date:  2010-10-25       Impact factor: 3.481

8.  Whole abdomen radiation therapy in ovarian cancers: a comparison between fixed beam and volumetric arc based intensity modulation.

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Journal:  Radiat Oncol       Date:  2010-11-15       Impact factor: 3.481

9.  Early clinical experience with volumetric modulated arc therapy in head and neck cancer patients.

Authors:  Marta Scorsetti; Antonella Fogliata; Simona Castiglioni; Caterina Bressi; Mario Bignardi; Piera Navarria; Pietro Mancosu; Luca Cozzi; Sara Pentimalli; Filippo Alongi; Armando Santoro
Journal:  Radiat Oncol       Date:  2010-10-15       Impact factor: 3.481

10.  Early clinical experience of radiotherapy of prostate cancer with volumetric modulated arc therapy.

Authors:  Gianfranco A Pesce; Alessandro Clivio; Luca Cozzi; Giorgia Nicolini; Antonella Richetti; Emanuela Salati; Mariacarla Valli; Eugenio Vanetti; Antonella Fogliata
Journal:  Radiat Oncol       Date:  2010-06-16       Impact factor: 3.481

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