| Literature DB >> 19422261 |
Hak Soo Choi1, Binil Itty Ipe, Preeti Misra, Jeong Heon Lee, Moungi G Bawendi, John V Frangioni.
Abstract
A significant portion of the field of nanomedicine is predicated on being able to target nanoparticles to sites of disease. However, in vivo biodistribution and clearance of nanoparticles are poorly understood. In this study, a novel formulation of near-infrared fluorescent InAs(ZnS) quantum dots was synthesized and coated with a systematically increasing chain length of PEG. We found that varying PEG chain length resulted in major changes in organ/tissue-selective biodistribution and clearance from the body.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19422261 PMCID: PMC2782558 DOI: 10.1021/nl900872r
Source DB: PubMed Journal: Nano Lett ISSN: 1530-6984 Impact factor: 11.189