Literature DB >> 17957183

Nanoparticles in medicine: therapeutic applications and developments.

L Zhang1, F X Gu, J M Chan, A Z Wang, R S Langer, O C Farokhzad.   

Abstract

Nanotechnology is the understanding and control of matter generally in the 1-100 nm dimension range. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities. Nanomaterials have unique physicochemical properties, such as ultra small size, large surface area to mass ratio, and high reactivity, which are different from bulk materials of the same composition. These properties can be used to overcome some of the limitations found in traditional therapeutic and diagnostic agents.

Mesh:

Year:  2007        PMID: 17957183     DOI: 10.1038/sj.clpt.6100400

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


  468 in total

1.  Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs.

Authors:  Udayanath Aich; M Adam Meledeo; Srinivasa-Gopalan Sampathkumar; Jie Fu; Mark B Jones; Christopher A Weier; Sung Yun Chung; Benjamin C Tang; Ming Yang; Justin Hanes; Kevin J Yarema
Journal:  Glycoconj J       Date:  2010-05-11       Impact factor: 2.916

2.  Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy.

Authors:  Nagesh Kolishetti; Shanta Dhar; Pedro M Valencia; Lucy Q Lin; Rohit Karnik; Stephen J Lippard; Robert Langer; Omid C Farokhzad
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

Review 3.  Nanochemoprevention: sustained release of bioactive food components for cancer prevention.

Authors:  Imtiaz A Siddiqui; Vaqar M Adhami; Nihal Ahmad; Hasan Mukhtar
Journal:  Nutr Cancer       Date:  2010       Impact factor: 2.900

4.  Evaluation of multivalent, functional polymeric nanoparticles for imaging applications.

Authors:  Monica Shokeen; Eric D Pressly; Aviv Hagooly; Alexander Zheleznyak; Nicholas Ramos; Ashley L Fiamengo; Michael J Welch; Craig J Hawker; Carolyn J Anderson
Journal:  ACS Nano       Date:  2011-01-28       Impact factor: 15.881

5.  In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles.

Authors:  Juliana M Chan; June-Wha Rhee; Chester L Drum; Roderick T Bronson; Gershon Golomb; Robert Langer; Omid C Farokhzad
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-15       Impact factor: 11.205

6.  Targeting the blind spot of polycationic nanocarrier-based siRNA delivery.

Authors:  Mengyao Zheng; Giovanni M Pavan; Manuel Neeb; Andreas K Schaper; Andrea Danani; Gerhard Klebe; Olivia M Merkel; Thomas Kissel
Journal:  ACS Nano       Date:  2012-10-09       Impact factor: 15.881

7.  Nanoparticles functionalized with collagenase exhibit improved tumor accumulation in a murine xenograft model.

Authors:  Surya Murty; Taylor Gilliland; Peter Qiao; Tate Tabtieng; Elizabeth Higbee; Ajlan Al Zaki; Ellen Puré; Andrew Tsourkas
Journal:  Part Part Syst Charact       Date:  2014-12       Impact factor: 3.310

Review 8.  Intelligent design of multifunctional lipid-coated nanoparticle platforms for cancer therapy.

Authors:  Srinivas Ramishetti; Leaf Huang
Journal:  Ther Deliv       Date:  2012-12

Review 9.  Nanoparticle-Based Therapies for Wound Biofilm Infection: Opportunities and Challenges.

Authors:  Min-Ho Kim
Journal:  IEEE Trans Nanobioscience       Date:  2016-03-02       Impact factor: 2.935

10.  Shrinkage of pegylated and non-pegylated liposomes in serum.

Authors:  Joy Wolfram; Krishna Suri; Yong Yang; Jianliang Shen; Christian Celia; Massimo Fresta; Yuliang Zhao; Haifa Shen; Mauro Ferrari
Journal:  Colloids Surf B Biointerfaces       Date:  2013-10-24       Impact factor: 5.268

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