BACKGROUND: Computer-aided detection (CAD) has been shown to increase the sensitivity for detection of pulmonary nodules in adults. This study reports initial findings utilizing a CAD system for the detection of pediatric pulmonary nodules. OBJECTIVE: To assess the performance of CAD and pediatric radiologists in the detection of pediatric pulmonary nodules. MATERIALS AND METHODS: CT scans from a series of pediatric patients with known primary tumors and lung nodules were analyzed by four radiologists and a commercially available CAD system. IRB approval was obtained. Sensitivities were calculated for detection according to nodule size and location. RESULTS: In 24 children (age 3-18 years) 173 nodules were identified. Overall the sensitivity of CAD was 34%, but the sensitivity of CAD for detection of nodules 4.0 mm or larger was 80%. Overall radiologist sensitivity ranged from 68% to 79%. There were 0.9 CAD false-positives and 0.3-2.4 radiologist false-positives per study. CONCLUSION: CAD in our pediatric oncology patients had good sensitivity for detection of lung nodules 4 mm and larger with a low number of false-positives. However, the sensitivity was considerably less for nodules smaller than 4 mm.
BACKGROUND: Computer-aided detection (CAD) has been shown to increase the sensitivity for detection of pulmonary nodules in adults. This study reports initial findings utilizing a CAD system for the detection of pediatric pulmonary nodules. OBJECTIVE: To assess the performance of CAD and pediatric radiologists in the detection of pediatric pulmonary nodules. MATERIALS AND METHODS: CT scans from a series of pediatric patients with known primary tumors and lung nodules were analyzed by four radiologists and a commercially available CAD system. IRB approval was obtained. Sensitivities were calculated for detection according to nodule size and location. RESULTS: In 24 children (age 3-18 years) 173 nodules were identified. Overall the sensitivity of CAD was 34%, but the sensitivity of CAD for detection of nodules 4.0 mm or larger was 80%. Overall radiologist sensitivity ranged from 68% to 79%. There were 0.9 CAD false-positives and 0.3-2.4 radiologist false-positives per study. CONCLUSION: CAD in our pediatric oncology patients had good sensitivity for detection of lung nodules 4 mm and larger with a low number of false-positives. However, the sensitivity was considerably less for nodules smaller than 4 mm.
Authors: Marco Das; Georg Mühlenbruch; Andreas H Mahnken; Thomas G Flohr; Lutz Gündel; Sven Stanzel; Thomas Kraus; Rolf W Günther; Joachim E Wildberger Journal: Radiology Date: 2006-11 Impact factor: 11.105
Authors: K Murata; M Takahashi; M Mori; N Kawaguchi; A Furukawa; Y Ohnaka; R Itoh; K Kawakami; Y Morioka; R Morita Journal: Radiology Date: 1992-02 Impact factor: 11.105
Authors: H Rusinek; D P Naidich; G McGuinness; B S Leitman; D I McCauley; G A Krinsky; K Clayton; H Cohen Journal: Radiology Date: 1998-10 Impact factor: 11.105
Authors: Atia Samim; Annemieke S Littooij; Marry M van den Heuvel-Eibrink; Frank J Wessels; Rutger A J Nievelstein; Pim A de Jong Journal: Pediatr Radiol Date: 2017-09-04