Literature DB >> 19412297

Are quantitative attenuation measurements of blood by optical coherence tomography feasible?

Dirk J Faber1, Ton G van Leeuwen.   

Abstract

We present optical coherence tomography (OCT) measurements on fully physiologically oxygenated blood samples of varying hematocrit. We show that attenuation coefficients cannot be extracted quantitatively using the currently accepted models for the OCT signal from scattering media, because the confidence intervals obtained in the fitting procedure cannot be used as reliable uncertainty estimates of the attenuation coefficients. Better modeling of the hematocrit-dependent OCT signal is needed.

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Year:  2009        PMID: 19412297     DOI: 10.1364/ol.34.001435

Source DB:  PubMed          Journal:  Opt Lett        ISSN: 0146-9592            Impact factor:   3.776


  22 in total

1.  Validation of quantitative attenuation and backscattering coefficient measurements by optical coherence tomography in the concentration-dependent and multiple scattering regime.

Authors:  Mitra Almasian; Nienke Bosschaart; Ton G van Leeuwen; Dirk J Faber
Journal:  J Biomed Opt       Date:  2015       Impact factor: 3.170

2.  Quantitative contrast-enhanced optical coherence tomography.

Authors:  Yonatan Winetraub; Elliott D SoRelle; Orly Liba; Adam de la Zerda
Journal:  Appl Phys Lett       Date:  2016-01-12       Impact factor: 3.791

3.  Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography.

Authors:  Shau Poh Chong; Conrad W Merkle; Conor Leahy; Harsha Radhakrishnan; Vivek J Srinivasan
Journal:  Biomed Opt Express       Date:  2015-03-24       Impact factor: 3.732

4.  Comment on "Quantitative comparison of analysis methods for spectroscopic optical coherence tomography".

Authors:  Maciej Kraszewski; Michał Trojanowski; Marcin R Strąkowski
Journal:  Biomed Opt Express       Date:  2014-08-12       Impact factor: 3.732

5.  Dual-wavelength photothermal optical coherence tomography for imaging microvasculature blood oxygen saturation.

Authors:  Biwei Yin; Roman V Kuranov; Austin B McElroy; Shams Kazmi; Andrew K Dunn; Timothy Q Duong; Thomas E Milner
Journal:  J Biomed Opt       Date:  2013-05       Impact factor: 3.170

6.  Comparison of different metrics for analysis and visualization in spectroscopic optical coherence tomography.

Authors:  Volker Jaedicke; Semih Agcaer; Francisco E Robles; Marian Steinert; David Jones; Sebastian Goebel; Nils C Gerhardt; Hubert Welp; Martin R Hofmann
Journal:  Biomed Opt Express       Date:  2013-11-22       Impact factor: 3.732

7.  Dual-band optical coherence tomography using a single supercontinuum laser source.

Authors:  Siyu Chen; Xiao Shu; Ji Yi; Amani Fawzi; Hao F Zhang
Journal:  J Biomed Opt       Date:  2016-06-01       Impact factor: 3.170

8.  Compartment-resolved imaging of cortical functional hyperemia with OCT angiography.

Authors:  Harsha Radhakrishnan; Vivek J Srinivasan
Journal:  Biomed Opt Express       Date:  2013-07-02       Impact factor: 3.732

9.  Molecular imaging true-colour spectroscopic optical coherence tomography.

Authors:  Francisco E Robles; Christy Wilson; Gerald Grant; Adam Wax
Journal:  Nat Photonics       Date:  2011-10-23       Impact factor: 38.771

10.  Apoptosis- and necrosis-induced changes in light attenuation measured by optical coherence tomography.

Authors:  Freek J van der Meer; Dirk J Faber; Maurice C G Aalders; Andre A Poot; Istvan Vermes; Ton G van Leeuwen
Journal:  Lasers Med Sci       Date:  2010-03       Impact factor: 3.161

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