Literature DB >> 19412189

Autoimmunity: CTLA-4: a key protein in autoimmunity.

Jagadeesh Bayry1.   

Abstract

Studies performed during the past 2 years have provided a deeper understanding into the role of CTLA-4, which is expressed on regulatory T cells, in preventing autoimmunity, and also provide mechanistic insight into protein-based therapeutics such as abatacept for rheumatic diseases.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19412189     DOI： 10.1038/nrrheum.2009.77

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN： 1759-4790            Impact factor:   20.543


  10 in total

1.  Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.

Authors:  Hironori Ueda; Joanna M M Howson; Laura Esposito; Joanne Heward; Hywel Snook; Giselle Chamberlain; Daniel B Rainbow; Kara M D Hunter; Annabel N Smith; Gianfranco Di Genova; Mathias H Herr; Ingrid Dahlman; Felicity Payne; Deborah Smyth; Christopher Lowe; Rebecca C J Twells; Sarah Howlett; Barry Healy; Sarah Nutland; Helen E Rance; Vin Everett; Luc J Smink; Alex C Lam; Heather J Cordell; Neil M Walker; Cristina Bordin; John Hulme; Costantino Motzo; Francesco Cucca; J Fred Hess; Michael L Metzker; Jane Rogers; Simon Gregory; Amit Allahabadia; Ratnasingam Nithiyananthan; Eva Tuomilehto-Wolf; Jaakko Tuomilehto; Polly Bingley; Kathleen M Gillespie; Dag E Undlien; Kjersti S Rønningen; Cristian Guja; Constantin Ionescu-Tîrgovişte; David A Savage; A Peter Maxwell; Dennis J Carson; Chris C Patterson; Jayne A Franklyn; David G Clayton; Laurence B Peterson; Linda S Wicker; John A Todd; Stephen C L Gough
Journal:  Nature       Date:  2003-04-30       Impact factor: 49.962

Review 2.  Monoclonal antibody and intravenous immunoglobulin therapy for rheumatic diseases: rationale and mechanisms of action.

Authors:  Jagadeesh Bayry; Sébastien Lacroix-Desmazes; Michel D Kazatchkine; Srini V Kaveri
Journal:  Nat Clin Pract Rheumatol       Date:  2007-05

Review 3.  Regulatory T cells and immune tolerance.

Authors:  Shimon Sakaguchi; Tomoyuki Yamaguchi; Takashi Nomura; Masahiro Ono
Journal:  Cell       Date:  2008-05-30       Impact factor: 41.582

Review 4.  Drug Insight: abatacept for the treatment of rheumatoid arthritis.

Authors:  Eric M Ruderman; Richard M Pope
Journal:  Nat Clin Pract Rheumatol       Date:  2006-12

5.  CTLA-4 control over Foxp3+ regulatory T cell function.

Authors:  Kajsa Wing; Yasushi Onishi; Paz Prieto-Martin; Tomoyuki Yamaguchi; Makoto Miyara; Zoltan Fehervari; Takashi Nomura; Shimon Sakaguchi
Journal:  Science       Date:  2008-10-10       Impact factor: 47.728

6.  Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis.

Authors:  Fabian Flores-Borja; Elizabeth C Jury; Claudia Mauri; Michael R Ehrenstein
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-26       Impact factor: 11.205

7.  Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation.

Authors:  Yasushi Onishi; Zoltan Fehervari; Tomoyuki Yamaguchi; Shimon Sakaguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-17       Impact factor: 11.205

8.  CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice.

Authors:  Paula Kolar; Karin Knieke; J Kolja E Hegel; Dagmar Quandt; Gerd-R Burmester; Holger Hoff; Monika C Brunner-Weinzierl
Journal:  Arthritis Rheum       Date:  2009-01

9.  Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants.

Authors:  Marta Barreto; Ricardo C Ferreira; Lara Lourenço; Maria F Moraes-Fontes; Eugénia Santos; Miguel Alves; Cláudia Carvalho; Berta Martins; Rita Andreia; João F Viana; Carlos Vasconcelos; Luísa Mota-Vieira; Carlos Ferreira; Jocelyne Demengeot; Astrid M Vicente
Journal:  BMC Immunol       Date:  2009-01-27       Impact factor: 3.615

10.  CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance.

Authors:  Randall H Friedline; David S Brown; Hai Nguyen; Hardy Kornfeld; Jinhee Lee; Yi Zhang; Mark Appleby; Sandy D Der; Joonsoo Kang; Cynthia A Chambers
Journal:  J Exp Med       Date:  2009-02-02       Impact factor: 14.307
  10 in total
  11 in total

Review 1.  Immunomodulation by intravenous immunoglobulin: role of regulatory T cells.

Authors:  Mohan S Maddur; Shivashankar Othy; Pushpa Hegde; Janakiraman Vani; Sébastien Lacroix-Desmazes; Jagadeesh Bayry; Srini V Kaveri
Journal:  J Clin Immunol       Date:  2010-05       Impact factor: 8.317

2.  Cooperative regulation of NOTCH1 protein-phosphatidylinositol 3-kinase (PI3K) signaling by NOD1, NOD2, and TLR2 receptors renders enhanced refractoriness to transforming growth factor-beta (TGF-beta)- or cytotoxic T-lymphocyte antigen 4 (CTLA-4)-mediated impairment of human dendritic cell maturation.

Authors:  Devram Sampat Ghorpade; Srini V Kaveri; Jagadeesh Bayry; Kithiganahalli Narayanaswamy Balaji
Journal:  J Biol Chem       Date:  2011-07-15       Impact factor: 5.157

Review 3.  Intravenous immunoglobulin therapy in rheumatic diseases.

Authors:  Jagadeesh Bayry; Vir Singh Negi; Srini V Kaveri
Journal:  Nat Rev Rheumatol       Date:  2011-05-10       Impact factor: 20.543

Review 4.  Targeted immunotherapy trials for idiopathic inflammatory myopathies.

Authors:  Joerg-Patrick Stübgen
Journal:  J Neurol       Date:  2012-06-30       Impact factor: 4.849

5.  Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks.

Authors:  Jacob W Freimer; Oren Shaked; Sahin Naqvi; Nasa Sinnott-Armstrong; Arwa Kathiria; Christian M Garrido; Amy F Chen; Jessica T Cortez; William J Greenleaf; Jonathan K Pritchard; Alexander Marson
Journal:  Nat Genet       Date:  2022-07-11       Impact factor: 41.307

Review 6.  Sex as an important factor in nanomedicine.

Authors:  Mohammah Javad Hajipour; Haniyeh Aghaverdi; Vahid Serpooshan; Hojatollah Vali; Sara Sheibani; Morteza Mahmoudi
Journal:  Nat Commun       Date:  2021-05-20       Impact factor: 14.919

7.  Viscum album exerts anti-inflammatory effect by selectively inhibiting cytokine-induced expression of cyclooxygenase-2.

Authors:  Pushpa Hegde; Mohan S Maddur; Alain Friboulet; Jagadeesh Bayry; Srini V Kaveri
Journal:  PLoS One       Date:  2011-10-18       Impact factor: 3.240

Review 8.  Immune checkpoint blockade opens an avenue of cancer immunotherapy with a potent clinical efficacy.

Authors:  Keishi Adachi; Koji Tamada
Journal:  Cancer Sci       Date:  2015-07-02       Impact factor: 6.716

9.  Disturbances of modulating molecules (FOXP3, CTLA-4/CD28/B7, and CD40/CD40L) mRNA expressions in the orbital tissue from patients with severe graves' ophthalmopathy.

Authors:  Przemyslaw Pawlowski; Natalia Wawrusiewicz-Kurylonek; Anja Eckstein; Joanna Reszec; Wlodzimierz Luczynski; Kristian Johnson; Adam Kretowski; Alina Bakunowicz-Lazarczyk; Maria Gorska; Jacek Szamatowicz; Lech Chyczewski; Janusz Mysliwiec
Journal:  Mediators Inflamm       Date:  2015-01-12       Impact factor: 4.711

10.  Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer.

Authors:  Maureen L Drakes; Swati Mehrotra; Monica Aldulescu; Ronald K Potkul; Yueying Liu; Anne Grisoli; Cara Joyce; Timothy E O'Brien; M Sharon Stack; Patrick J Stiff
Journal:  J Ovarian Res       Date:  2018-05-30       Impact factor: 4.234
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.