Literature DB >> 19410538

Ure(k)a! Sirtuins Regulate Mitochondria.

William C Hallows1, Brian C Smith, Susan Lee, John M Denu.   

Abstract

Increasing evidence suggests that multiple metabolic pathways are regulated by sirtuin-dependent protein deacetylation in the mitochondria. In this issue, Nakagawa et al. (2009) show that the sirtuin SIRT5 deacetylates and activates a mitochondrial enzyme, carbamoyl phosphate synthetase 1, which mediates the first step in the urea cycle.

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Year:  2009        PMID： 19410538      PMCID： PMC3310393          DOI： 10.1016/j.cell.2009.04.036

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.

Authors:  Sung Chan Kim; Robert Sprung; Yue Chen; Yingda Xu; Haydn Ball; Jimin Pei; Tzuling Cheng; Yoonjung Kho; Hao Xiao; Lin Xiao; Nick V Grishin; Michael White; Xiang-Jiao Yang; Yingming Zhao
Journal:  Mol Cell       Date:  2006-08       Impact factor: 17.970

2.  Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases.

Authors:  William C Hallows; Susan Lee; John M Denu
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-21       Impact factor: 11.205

3.  SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.

Authors:  Marcia C Haigis; Raul Mostoslavsky; Kevin M Haigis; Kamau Fahie; Danos C Christodoulou; Andrew J Murphy; David M Valenzuela; George D Yancopoulos; Margaret Karow; Gil Blander; Cynthia Wolberger; Tomas A Prolla; Richard Weindruch; Frederick W Alt; Leonard Guarente
Journal:  Cell       Date:  2006-09-08       Impact factor: 41.582

4.  Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.

Authors:  David B Lombard; Frederick W Alt; Hwei-Ling Cheng; Jakob Bunkenborg; Ryan S Streeper; Raul Mostoslavsky; Jennifer Kim; George Yancopoulos; David Valenzuela; Andrew Murphy; Yinhua Yang; Yaohui Chen; Matthew D Hirschey; Roderick T Bronson; Marcia Haigis; Leonard P Guarente; Robert V Farese; Sherman Weissman; Eric Verdin; Bjoern Schwer
Journal:  Mol Cell Biol       Date:  2007-10-08       Impact factor: 4.272

5.  Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.

Authors:  Christine Schlicker; Melanie Gertz; Panagiotis Papatheodorou; Barbara Kachholz; Christian F W Becker; Clemens Steegborn
Journal:  J Mol Biol       Date:  2008-07-25       Impact factor: 5.469

6.  A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis.

Authors:  Bong-Hyun Ahn; Hyun-Seok Kim; Shiwei Song; In Hye Lee; Jie Liu; Athanassios Vassilopoulos; Chu-Xia Deng; Toren Finkel
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-15       Impact factor: 11.205

7.  Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival.

Authors:  Hongying Yang; Tianle Yang; Joseph A Baur; Evelyn Perez; Takashi Matsui; Juan J Carmona; Dudley W Lamming; Nadja C Souza-Pinto; Vilhelm A Bohr; Anthony Rosenzweig; Rafael de Cabo; Anthony A Sauve; David A Sinclair
Journal:  Cell       Date:  2007-09-21       Impact factor: 41.582

Review 8.  Mechanisms and molecular probes of sirtuins.

Authors:  Brian C Smith; William C Hallows; John M Denu
Journal:  Chem Biol       Date:  2008-10-20

9.  SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle.

Authors:  Takashi Nakagawa; David J Lomb; Marcia C Haigis; Leonard Guarente
Journal:  Cell       Date:  2009-05-01       Impact factor: 41.582
  9 in total
  10 in total

Review 1.  The redox basis of epigenetic modifications: from mechanisms to functional consequences.

Authors:  Anthony R Cyr; Frederick E Domann
Journal:  Antioxid Redox Signal       Date:  2011-02-05       Impact factor: 8.401

2.  Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice.

Authors:  Kristofer S Fritz; James J Galligan; Matthew D Hirschey; Eric Verdin; Dennis R Petersen
Journal:  J Proteome Res       Date:  2012-02-21       Impact factor: 4.466

Review 3.  The Mitochondrion as an Emerging Therapeutic Target in Cancer.

Authors:  Katherine G Roth; Isa Mambetsariev; Prakash Kulkarni; Ravi Salgia
Journal:  Trends Mol Med       Date:  2019-07-18       Impact factor: 11.951

Review 4.  Computational modeling of mitochondrial energy transduction.

Authors:  J P J Schmitz; J Vanlier; N A W van Riel; Jeroen A L Jeneson
Journal:  Crit Rev Biomed Eng       Date:  2011

5.  Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.

Authors:  Dawei Chen; Melanie Vollmar; Marianna N Rossi; Claire Phillips; Rolf Kraehenbuehl; Dea Slade; Pawan V Mehrotra; Frank von Delft; Susan K Crosthwaite; Opher Gileadi; John M Denu; Ivan Ahel
Journal:  J Biol Chem       Date:  2011-01-21       Impact factor: 5.157

6.  Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties.

Authors:  Francis C Peterson; Dawei Chen; Betsy L Lytle; Marianna N Rossi; Ivan Ahel; John M Denu; Brian F Volkman
Journal:  J Biol Chem       Date:  2011-08-17       Impact factor: 5.157

7.  Anshen-Buxin-Liuwei pill, a Mongolian medicinal formula could alleviate cardiomyocyte hypoxia/reoxygenation injury via mitochondrion pathway.

Authors:  Yu-Jia Huang; Hai-Ying Tong; Xian-Ju Huang; Xin-Cai Xiao; Yue Dong; Muhammad Sarfaraz Iqbal
Journal:  Mol Biol Rep       Date:  2022-01-10       Impact factor: 2.316

Review 8.  Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction.

Authors:  Saskia Koene; Jan Smeitink
Journal:  J Inherit Metab Dis       Date:  2010-07-29       Impact factor: 4.982

9.  SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo.

Authors:  Xiuli Yi; Weinan Guo; Qiong Shi; Yuqi Yang; Weigang Zhang; Xuguang Chen; Pan Kang; Jiaxi Chen; Tingting Cui; Jinyuan Ma; Huina Wang; Sen Guo; Yuqian Chang; Ling Liu; Zhe Jian; Lin Wang; Qian Xiao; Shuli Li; Tianwen Gao; Chunying Li
Journal:  Theranostics       Date:  2019-02-28       Impact factor: 11.556

10.  Jian-Pi-Yi-Shen Formula Alleviates Chronic Kidney Disease in Two Rat Models by Modulating QPRT/NAD+/SIRT3/Mitochondrial Dynamics Pathway.

Authors:  Xinhui Liu; Siqi Liu; Bing Zhang; Denggui Luo; Shiying Huang; Fochang Wang; Lin Zheng; Jiandong Lu; Jianping Chen; Shunmin Li
Journal:  Evid Based Complement Alternat Med       Date:  2021-12-13       Impact factor: 2.629
  10 in total

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