Literature DB >> 1940960

Effects of CDP-choline on the recovery of patients with head injury.

V Calatayud Maldonado1, J B Calatayud Pérez, J Aso Escario.   

Abstract

A single blind randomized study has been conducted in 216 patients with severe or moderate head injury, with the aim of comparing the evolution of those that received only conventional treatment with the evolution of those treated with CDP-choline. Our results indicate that CDP-choline improves the global outcome of patients. We have found a trend towards a greater improvement in motor, cognitive and psychic alterations in the patients treated with CDP-choline, as well as a shortening of the stay in the hospital ward in the patients receiving this drug that initially presented with severe head injuries.

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Year:  1991        PMID: 1940960     DOI: 10.1016/0022-510x(91)90003-p

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  15 in total

Review 1.  Therapies targeting lipid peroxidation in traumatic brain injury.

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Journal:  Brain Res       Date:  2016-02-10       Impact factor: 3.252

2.  Citicoline in severe traumatic brain injury: indications for improved outcome : A retrospective matched pair analysis from 14 Austrian trauma centers.

Authors:  Helmut Trimmel; Marek Majdan; Andrea Wodak; Guenther Herzer; Daniel Csomor; Alexandra Brazinova
Journal:  Wien Klin Wochenschr       Date:  2017-07-27       Impact factor: 1.704

Review 3.  A meta-analysis of the effect of different neuroprotective drugs in management of patients with traumatic brain injury.

Authors:  Iman El Sayed; Adel Zaki; Akram M Fayed; Gihan M Shehata; Sherif Abdelmonem
Journal:  Neurosurg Rev       Date:  2016-08-18       Impact factor: 3.042

4.  Phospholipid biosynthetic enzymes in human brain.

Authors:  B M Ross; A Moszczynska; J K Blusztajn; A Sherwin; A Lozano; S J Kish
Journal:  Lipids       Date:  1997-04       Impact factor: 1.880

5.  Eight weeks of citicoline treatment does not perturb sleep/wake cycles in cocaine-dependent adults.

Authors:  Bethany K Bracken; David M Penetar; John Rodolico; Elizabeth T Ryan; Scott E Lukas
Journal:  Pharmacol Biochem Behav       Date:  2011-03-21       Impact factor: 3.533

6.  Treatment of post-traumatic cognitive impairments.

Authors:  Hal S Wortzel; David B Arciniegas
Journal:  Curr Treat Options Neurol       Date:  2012-10       Impact factor: 3.598

7.  The citicoline brain injury treatment (COBRIT) trial: design and methods.

Authors:  Ross Zafonte; William T Friedewald; Shing M Lee; Bruce Levin; Ramon Diaz-Arrastia; Beth Ansel; Howard Eisenberg; Shelly D Timmons; Nancy Temkin; Thomas Novack; Joseph Ricker; Randall Merchant; Jack Jallo
Journal:  J Neurotrauma       Date:  2009-12       Impact factor: 5.269

Review 8.  Role of Citicoline in the Management of Traumatic Brain Injury.

Authors:  Julio J Secades
Journal:  Pharmaceuticals (Basel)       Date:  2021-04-26

9.  Serum metabolome associated with severity of acute traumatic brain injury.

Authors:  Ilias Thomas; Alex M Dickens; Jussi P Posti; Endre Czeiter; Daniel Duberg; Tim Sinioja; Matilda Kråkström; Isabel R A Retel Helmrich; Kevin K W Wang; Andrew I R Maas; Ewout W Steyerberg; David K Menon; Olli Tenovuo; Tuulia Hyötyläinen; András Büki; Matej Orešič
Journal:  Nat Commun       Date:  2022-05-10       Impact factor: 17.694

10.  Mild traumatic brain injury: a neuropsychiatric approach to diagnosis, evaluation, and treatment.

Authors:  David B Arciniegas; C Alan Anderson; Jeannie Topkoff; Thomas W McAllister
Journal:  Neuropsychiatr Dis Treat       Date:  2005-12       Impact factor: 2.570

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