Wang-Cheng Ko1, Yu-Fu Chen. 1. Department of Dermatology, Show-Chwan Memorial Hospital, Chang-Hua, Taiwan.
Abstract
BACKGROUND: Despite the availability of various new methods to treat vitiligo, surgical methods offer rapid, simple, and safe ways for treating small-sized vitiligo. OBJECTIVE: To evaluate the feasibility and efficacy in treating vitiligo using suction blister epidermal grafting (SBEG) combined with CO2 laser epidermal ablation. METHODS: Forty patients with small, stable vitiligo were treated using SBEG combined with CO2 laser epidermal ablation and followed up for at least 6 months and up to 10 years. RESULTS: Treatment outcomes were excellent for 32 patients (80%), good for four patients (10%), fair for three patients (7.5%), and poor for one patient (2.5%). No scar formation was observed in any patients. Location of the lesions was probably the most important factor in determining the outcomes of transplantation. CONCLUSION: This study suggests that SBEG combined with CO2 laser ablation is a rapid, simple, and safe method to treat vitiligo, especially for patients with small and stable vitiliginous lesions.
BACKGROUND: Despite the availability of various new methods to treat vitiligo, surgical methods offer rapid, simple, and safe ways for treating small-sized vitiligo. OBJECTIVE: To evaluate the feasibility and efficacy in treating vitiligo using suction blister epidermal grafting (SBEG) combined with CO2 laser epidermal ablation. METHODS: Forty patients with small, stable vitiligo were treated using SBEG combined with CO2 laser epidermal ablation and followed up for at least 6 months and up to 10 years. RESULTS: Treatment outcomes were excellent for 32 patients (80%), good for four patients (10%), fair for three patients (7.5%), and poor for one patient (2.5%). No scar formation was observed in any patients. Location of the lesions was probably the most important factor in determining the outcomes of transplantation. CONCLUSION: This study suggests that SBEG combined with CO2 laser ablation is a rapid, simple, and safe method to treat vitiligo, especially for patients with small and stable vitiliginous lesions.
Authors: N F Post; N Ezekwe; V S Narayan; M W Bekkenk; N Van Geel; I Hamzavi; T Passeron; A Wolkerstorfer Journal: J Eur Acad Dermatol Venereol Date: 2022-03-01 Impact factor: 9.228