| Literature DB >> 19398816 |
Song Ge1, Xiangyang Shi, James R Baker, Mark M Banaszak Holl, Bradford G Orr.
Abstract
We present a remanence measurement method using a superconducting quantum interference device (SQUID) to detect trace amounts of magnetic nanoparticles (MNPs). Based on this method, a one-dimensional scanning system was established for imaging. The system was calibrated with 25 nm diameter Fe2O3 nanoparticles (NPs), and the sensitivity of the NPs was found to be 10 ng at a distance of 1.7 cm and the spatial resolution was approximately 1 cm. A theoretical model of this system was developed and applied to the deconvolution of scanned images of phantoms with two NP injection spots. Using the developed SQUID system, we were able to determine not only the amount and horizontal positions of the injections, but also their depths in the phantoms.Entities:
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Year: 2009 PMID: 19398816 PMCID: PMC2726008 DOI: 10.1088/0031-9155/54/10/N01
Source DB: PubMed Journal: Phys Med Biol ISSN: 0031-9155 Impact factor: 3.609