OBJECTIVE: To explore the relationship between three QEEG global indexes and their association with functional outcome after neurorehabilitation in non-acute acquired brain injury (ABI) patients (traumatic brain injury and stroke). METHODS: Twenty-one adult ABI patients in post-acute phase were studied. Delta-alpha ratio (DAR), Power Ratio Index (PRI) and Mean Brain Symmetry Index (mBSI) were calculated from resting-state EEG taken at admission. These indexes and other clinical variables were correlated with functional recovery achieved after six months of neurorehabilitation. RESULTS: DAR showed the highest strength of association with the functional outcome measure (rho=-0.65, P=0.002). The other QEEG indexes and clinical variables showed modest non-significant correlations. A posteriori group analysis showed higher DAR in patients with poor recovery as compared to good recovery patients. CONCLUSIONS: Functional recovery after neurorehabilitation appears to be associated with a number of clinical and neurophysiological variables. Among the latter, the ratio between delta and alpha may play a significant role in predicting and monitoring functional rehabilitation outcome. SIGNIFICANCE: Neurophysiological assessment of ABI patients may be an important tool in monitoring and predicting outcomes after neurorehabilitation.
OBJECTIVE: To explore the relationship between three QEEG global indexes and their association with functional outcome after neurorehabilitation in non-acute acquired brain injury (ABI) patients (traumatic brain injury and stroke). METHODS: Twenty-one adult ABI patients in post-acute phase were studied. Delta-alpha ratio (DAR), Power Ratio Index (PRI) and Mean Brain Symmetry Index (mBSI) were calculated from resting-state EEG taken at admission. These indexes and other clinical variables were correlated with functional recovery achieved after six months of neurorehabilitation. RESULTS: DAR showed the highest strength of association with the functional outcome measure (rho=-0.65, P=0.002). The other QEEG indexes and clinical variables showed modest non-significant correlations. A posteriori group analysis showed higher DAR in patients with poor recovery as compared to good recovery patients. CONCLUSIONS: Functional recovery after neurorehabilitation appears to be associated with a number of clinical and neurophysiological variables. Among the latter, the ratio between delta and alpha may play a significant role in predicting and monitoring functional rehabilitation outcome. SIGNIFICANCE: Neurophysiological assessment of ABI patients may be an important tool in monitoring and predicting outcomes after neurorehabilitation.
Authors: Franck Amyot; David B Arciniegas; Michael P Brazaitis; Kenneth C Curley; Ramon Diaz-Arrastia; Amir Gandjbakhche; Peter Herscovitch; Sidney R Hinds; Geoffrey T Manley; Anthony Pacifico; Alexander Razumovsky; Jason Riley; Wanda Salzer; Robert Shih; James G Smirniotopoulos; Derek Stocker Journal: J Neurotrauma Date: 2015-09-30 Impact factor: 5.269
Authors: Leighton B N Hinkley; Elysa J Marco; Anne M Findlay; Susanne Honma; Rita J Jeremy; Zoe Strominger; Polina Bukshpun; Mari Wakahiro; Warren S Brown; Lynn K Paul; A James Barkovich; Pratik Mukherjee; Srikantan S Nagarajan; Elliott H Sherr Journal: PLoS One Date: 2012-08-03 Impact factor: 3.240