Latent variable path analysis in clinical research: a beginner's tour guide.

Latent variable path analysis (LVPA) is undoubtedly one of "the" new statistical techniques being used increasingly often by clinical researchers. Although well suited for some types of clinical research, LVPA can be a somewhat intimidating technique for novices. This work is intended to provide a non-mathematical introduction to the advantages and problems of LVPA for clinical researchers who are not yet familiar with this powerful procedure. The conceptual bases of LVPA, its relation to other statistical techniques, and possible uses and misuses in clinical research are considered. Many practical recommendations for the appropriate use of LVPA also are offered, as is a suggested reading list for researchers who wish to learn more about LVPA and related approaches.