Literature DB >> 19394172

Age and gender differences in blood-alcohol concentration in apprehended drivers in relation to the amounts of alcohol consumed.

Alan Wayne Jones1, Anita Holmgren.   

Abstract

This article reports the age, gender, and blood-alcohol concentration (BAC) of people apprehended in Sweden for driving under the influence of alcohol (DUIA) over an 8-year period (2000-2007). Duplicate determinations of ethanol were made in venous blood by headspace gas chromatography and results were reported positive at a cut-off concentration of 0.1 g/L (10 mg/100 ml or 0.01 g%). The mean, median and highest BAC was 1.74 g/L, 1.70 g/L and 5.18 g/L, respectively. The vast majority of offenders were men (89.5%) with a mean age of 39.0+/-14.6 y (+/-SD). The women (10.5%) were a few years older 41.8+/-13.6 y (p<0.001). The mean BAC in the men (1.73+/-0.85 g/L) did not differ significantly (p>0.05) from women (1.77+/-0.87 g/L). The youngest offenders aged 15-20 y (N=3513) had a mean BAC of 1.30+/-0.60 g/L (median 1.32), which was significantly less (p<0.001) than people aged 40-50 y (N=6644); mean 1.90 g/L (median 2.0 g/L). In 95 individuals (89 men and 6 women) the BAC exceeded 4.0 g/L, which is a level considered to cause death by acute alcohol poisoning. The Widmark formula was used to calculate that a man (80 kg) with a BAC of 1.7 g/L has 95 g ethanol (approximately 12 units of alcohol) in the body compared with 61 g (approximately 8 units) for a woman (60 kg). This study verifies that the average drunken driver in Sweden is typically a binge drinker and education programs and treatment for alcohol-use disorder might be a more appropriate sanction than the more conventional penalties for alcohol-impaired driving.

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Year:  2009        PMID: 19394172     DOI: 10.1016/j.forsciint.2009.03.010

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  14 in total

1.  Innate immunity and inflammation in sepsis: mechanisms of suppressed host resistance in mice treated with ethanol in a binge-drinking model.

Authors:  Stephen B Pruett; Ruping Fan; Bing Cheng; Mitzi Glover; Wei Tan; Xiaomin Deng
Journal:  Toxicol Sci       Date:  2010-07-12       Impact factor: 4.849

2.  Binge alcohol consumption 18 h after induction of sepsis in a mouse model causes rapid overgrowth of bacteria, a cytokine storm, and decreased survival.

Authors:  Minny Bhatty; Wei Tan; Maria Basco; Stephen Pruett; Bindu Nanduri
Journal:  Alcohol       Date:  2016-11-27       Impact factor: 2.405

3.  Developmental alterations in olivary climbing fiber distribution following postnatal ethanol exposure in the rat.

Authors:  D R Pierce; A Hayar; D K Williams; K E Light
Journal:  Neuroscience       Date:  2010-06-11       Impact factor: 3.590

4.  Role of acute ethanol exposure and TLR4 in early events of sepsis in a mouse model.

Authors:  Minny Bhatty; Basit L Jan; Wei Tan; Stephen B Pruett; Bindu Nanduri
Journal:  Alcohol       Date:  2011-08-27       Impact factor: 2.405

5.  Transgenerational effects of binge drinking in a primate model: implications for human health.

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Review 6.  Binge ethanol and liver: new molecular developments.

Authors:  Shivendra D Shukla; Stephen B Pruett; Gyongyi Szabo; Gavin E Arteel
Journal:  Alcohol Clin Exp Res       Date:  2013-01-24       Impact factor: 3.455

7.  Effects of oxidative alcohol metabolism on the mitochondrial permeability transition pore and necrosis in a mouse model of alcoholic pancreatitis.

Authors:  Natalia Shalbueva; Olga A Mareninova; Andreas Gerloff; Jingzhen Yuan; Richard T Waldron; Stephen J Pandol; Anna S Gukovskaya
Journal:  Gastroenterology       Date:  2012-10-24       Impact factor: 22.682

8.  Relationships of alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genotypes with alcohol sensitivity, drinking behavior and problem drinking in Japanese older men.

Authors:  Marowa Hashimoto; Masutaka Watanabe; Yuji Uematsu; Sonomi Hattori; Nobuyuki Miyai; Miyoko Utsumi; Mayumi Oka; Mariko Hayashida; Kenji Kinoshita; Mikio Arita; Tatsuya Takeshita
Journal:  Environ Health Prev Med       Date:  2016-01-29       Impact factor: 3.674

9.  Intracellular Invasion and Killing Assay to Investigate the Effectsof Binge Alcohol Toxicity in Murine Alveolar Macrophages.

Authors:  Victor Jimenez; Fernando P Monroy
Journal:  Bio Protoc       Date:  2019-01-20

10.  Ethanol transiently suppresses choline-acetyltransferase in basal nucleus of Meynert slices.

Authors:  Daniela Ehrlich; Michael Pirchl; Christian Humpel
Journal:  Brain Res       Date:  2012-04-20       Impact factor: 3.252

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