| Literature DB >> 19393695 |
Xiangyun He1, Jufang Wang, Jennifer Steele, Xingmin Sun, Weijia Nie, Saul Tzipori, Hanping Feng.
Abstract
We describe a novel ultrasensitive cell-based immunocytotoxicity assay for detecting Clostridium difficile toxin A and B. The assay is simple to perform with a turnaround time of approximately 3 h . It is particularly sensitive in detecting TcdA at a level less then 1 pg/ml. Using this assay, we were able to detect the presence of C. difficile toxins in the fecal and serum specimens of experimentally infected piglets.Entities:
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Year: 2009 PMID： 19393695 PMCID： PMC2740367 DOI： 10.1016/j.mimet.2009.04.007
Source DB: PubMed Journal: J Microbiol Methods ISSN： 0167-7012 Impact factor: 2.363