| Literature DB >> 1938972 |
Abstract
As a first step toward developing the genetic potential of extremely thermophilic archaebacteria, mutant strains of Sulfolobus acidocaldarius were selected by plating cells directly on solid medium containing one of several growth inhibitors. Three spontaneous resistance phenotypes were observed (5-fluorouracil resistance, novobiocin resistance, and L-ethionine resistance), each at a different average frequency. Characterization of representative strains showed each of the three mutant phenotypes to provide a potentially useful genetic marker.Entities:
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Year: 1991 PMID: 1938972 PMCID: PMC212547 DOI: 10.1128/jb.173.23.7725-7727.1991
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490