| Literature DB >> 19386484 |
Edward N Trifonov1, Zakharia M Frenkel.
Abstract
Proteins in their evolution appear to follow several discrete stages, which is reflected in their modular organization. The sequences of the protein modules are highly variable while their functions and structures are rather conserved. The relatedness of the variable sequences is well represented by the networks in natural protein sequence space that also suggests evolutionary connections.Mesh：
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Year: 2009 PMID： 19386484 DOI： 10.1016/j.sbi.2009.03.007
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809