Literature DB >> 19384879

Drug/dye-loaded, multifunctional iron oxide nanoparticles for combined targeted cancer therapy and dual optical/magnetic resonance imaging.

Santimukul Santra1, Charalambos Kaittanis, Jan Grimm, J Manuel Perez.   

Abstract

A biocompatible, multimodal, and theranostic functional iron oxide nanoparticle is synthesized using a novel water-based method and exerts excellent properties for targeted cancer therapy, and optical and magnetic resonance imaging. For the first time, a facile, modified solvent diffusion method is used for the co-encapsulation of both an anticancer drug and near-infrared dyes. The resulting folate-derivatized theranostics nanoparticles could allow for targeted optical/magnetic resonance imaging and targeted killing of folate-expressing cancer cells.

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Year:  2009        PMID： 19384879      PMCID： PMC3057065          DOI： 10.1002/smll.200900389

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  26 in total

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Journal:  Nat Med       Date:  2003-01       Impact factor: 53.440

2.  Multimodal biomedical imaging with asymmetric single-walled carbon nanotube/iron oxide nanoparticle complexes.

Authors:  Jong Hyun Choi; Freddy T Nguyen; Paul W Barone; Daniel A Heller; Anthonie E Moll; Dhaval Patel; Stephen A Boppart; Michael S Strano
Journal:  Nano Lett       Date:  2007-03-03       Impact factor: 11.189

3.  Immuno-polymeric nanoparticles by Diels-Alder chemistry.

Authors:  Meng Shi; Jordan H Wosnick; Karyn Ho; Armand Keating; Molly S Shoichet
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

4.  Antibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imaging.

Authors:  Haerim Lee; Eunhye Lee; Do Kyung Kim; Nam Kyu Jang; Yong Yeon Jeong; Sangyong Jon
Journal:  J Am Chem Soc       Date:  2006-06-07       Impact factor: 15.419

5.  Polymeric nanoparticle preparation that eradicates tumors.

Authors:  Jason R McCarthy; J Manuel Perez; Christian Brückner; Ralph Weissleder
Journal:  Nano Lett       Date:  2005-12       Impact factor: 11.189

6.  Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems.

Authors:  Norased Nasongkla; Erik Bey; Jimin Ren; Hua Ai; Chalermchai Khemtong; Jagadeesh Setti Guthi; Shook-Fong Chin; A Dean Sherry; David A Boothman; Jinming Gao
Journal:  Nano Lett       Date:  2006-11       Impact factor: 11.189

7.  Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay.

Authors:  Nikki Parker; Mary Jo Turk; Elaine Westrick; Jeffrey D Lewis; Philip S Low; Christopher P Leamon
Journal:  Anal Biochem       Date:  2005-03-15       Impact factor: 3.365

8.  Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells.

Authors:  Hong Yuan; Jing Miao; Yong-Zhong Du; Jian You; Fu-Qiang Hu; Su Zeng
Journal:  Int J Pharm       Date:  2007-07-18       Impact factor: 5.875

9.  Folate conjugated fluorescent silica nanoparticles for labeling neoplastic cells.

Authors:  Swadeshmukul Santra; Bernd Liesenfeld; Debamitra Dutta; David Chatel; Christopher D Batich; Weihong Tan; Brij M Moudgil; Robert A Mericle
Journal:  J Nanosci Nanotechnol       Date:  2005-06

10.  Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells.

Authors:  A M Koch; F Reynolds; M F Kircher; H P Merkle; R Weissleder; L Josephson
Journal:  Bioconjug Chem       Date:  2003 Nov-Dec       Impact factor: 4.774
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  83 in total

1.  Cytochrome C encapsulating theranostic nanoparticles: a novel bifunctional system for targeted delivery of therapeutic membrane-impermeable proteins to tumors and imaging of cancer therapy.

Authors:  Santimukul Santra; Charalambos Kaittanis; J Manuel Perez
Journal:  Mol Pharm       Date:  2010-08-02       Impact factor: 4.939

Review 2.  Responsive theranostic systems: integration of diagnostic imaging agents and responsive controlled release drug delivery carriers.

Authors:  Mary E Caldorera-Moore; William B Liechty; Nicholas A Peppas
Journal:  Acc Chem Res       Date:  2011-09-20       Impact factor: 22.384

Review 3.  Theranostic nanoplatforms for simultaneous cancer imaging and therapy: current approaches and future perspectives.

Authors:  Ki Young Choi; Gang Liu; Seulki Lee; Xiaoyuan Chen
Journal:  Nanoscale       Date:  2011-12-01       Impact factor: 7.790

Review 4.  Imaging and drug delivery using theranostic nanoparticles.

Authors:  Siti M Janib; Ara S Moses; J Andrew MacKay
Journal:  Adv Drug Deliv Rev       Date:  2010-08-13       Impact factor: 15.470

Review 5.  Quantum dot-based theranostics.

Authors:  Yi-Ping Ho; Kam W Leong
Journal:  Nanoscale       Date:  2009-10-06       Impact factor: 7.790

6.  Near Infrared Fluorescent Nanoplatform for Targeted Intraoperative Resection and Chemotherapeutic Treatment of Glioblastoma.

Authors:  Derek Reichel; Bien Sagong; James Teh; Yi Zhang; Shawn Wagner; Hongqiang Wang; Leland W K Chung; Pramod Butte; Keith L Black; John S Yu; J Manuel Perez
Journal:  ACS Nano       Date:  2020-06-23       Impact factor: 15.881

7.  Composite fluorescent nanoparticles for biomedical imaging.

Authors:  Vikram J Pansare; Matthew J Bruzek; Douglas H Adamson; John Anthony; Robert K Prud'homme
Journal:  Mol Imaging Biol       Date:  2014-04       Impact factor: 3.488

Review 8.  Enabling individualized therapy through nanotechnology.

Authors:  Jason H Sakamoto; Anne L van de Ven; Biana Godin; Elvin Blanco; Rita E Serda; Alessandro Grattoni; Arturas Ziemys; Ali Bouamrani; Tony Hu; Shivakumar I Ranganathan; Enrica De Rosa; Jonathan O Martinez; Christine A Smid; Rachel M Buchanan; Sei-Young Lee; Srimeenakshi Srinivasan; Matthew Landry; Anne Meyn; Ennio Tasciotti; Xuewu Liu; Paolo Decuzzi; Mauro Ferrari
Journal:  Pharmacol Res       Date:  2010-01-05       Impact factor: 7.658

9.  Aliphatic hyperbranched polyester: a new building block in the construction of multifunctional nanoparticles and nanocomposites.

Authors:  Santimukul Santra; Charalambos Kaittanis; J Manuel Perez
Journal:  Langmuir       Date:  2010-04-20       Impact factor: 3.882

10.  Dual-imaging enabled cancer-targeting nanoparticles.

Authors:  Aniket S Wadajkar; Tejaswi Kadapure; Yi Zhang; Weina Cui; Kytai T Nguyen; Jian Yang
Journal:  Adv Healthc Mater       Date:  2012-07       Impact factor: 9.933
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