Literature DB >> 19383389

Signaling networks in hepatic oval cell activation.

Laura Erker1, Markus Grompe.   

Abstract

Oval cells are hypothesized to be the progeny of intrahepatic stem cells, also referred to as adult liver stem cells. The mechanisms by which these cells are activated to proliferate and differentiate during liver regeneration is important for the development of new therapies to treat liver disease. Oval cell activation is the first step in progenitor-dependent liver regeneration in response to certain types of injury. This review describes what is currently known about the factors involved in oval cell activation, proliferation, migration, and differentiation.

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Year:  2008        PMID： 19383389     DOI： 10.1016/j.scr.2008.01.002

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN： 1873-5061            Impact factor:   2.020


  22 in total

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Authors:  Kimberly J Riehle; Yock Y Dan; Jean S Campbell; Nelson Fausto
Journal:  J Gastroenterol Hepatol       Date:  2011-01       Impact factor: 4.029

Review 2.  Biology of the adult hepatic progenitor cell: "ghosts in the machine".

Authors:  Houda Darwiche; Bryon E Petersen
Journal:  Prog Mol Biol Transl Sci       Date:  2010       Impact factor: 3.622

Review 3.  Minireview: beta-cell replacement therapy for diabetes in the 21st century: manipulation of cell fate by directed differentiation.

Authors:  Vijay Yechoor; Lawrence Chan
Journal:  Mol Endocrinol       Date:  2010-03-10

4.  Model systems and clinical applications of hepatic stem cells for liver regeneration.

Authors:  Min Zhang; Yan Zhong; Jun Chen
Journal:  Hepatol Int       Date:  2011-12-21       Impact factor: 6.047

5.  Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.

Authors:  Sayeepriyadarshini Anakk; Mitsuhiro Watanabe; Scott A Ochsner; Neil J McKenna; Milton J Finegold; David D Moore
Journal:  J Clin Invest       Date:  2010-12-01       Impact factor: 14.808

6.  FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration.

Authors:  Hinako M Takase; Tohru Itoh; Seitaro Ino; Ting Wang; Takehiko Koji; Shizuo Akira; Yasuhiro Takikawa; Atsushi Miyajima
Journal:  Genes Dev       Date:  2013-01-15       Impact factor: 11.361

Review 7.  Environmental exposures, stem cells, and cancer.

Authors:  Tasha Thong; Chanese A Forté; Evan M Hill; Justin A Colacino
Journal:  Pharmacol Ther       Date:  2019-07-31       Impact factor: 12.310

Review 8.  Stem cells and liver regeneration.

Authors:  Andrew W Duncan; Craig Dorrell; Markus Grompe
Journal:  Gastroenterology       Date:  2009-05-24       Impact factor: 22.682

9.  Two-tier regenerative response in liver failure in humans.

Authors:  Archana Rastogi; Rakhi Maiwall; Chhagan Bihari; Nirupma Trehanpati; Viniyendra Pamecha; Shiv Kumar Sarin
Journal:  Virchows Arch       Date:  2014-03-04       Impact factor: 4.064

10.  Podoplanin discriminates distinct stromal cell populations and a novel progenitor subset in the liver.

Authors:  Christoph Eckert; Yong Ook Kim; Henrike Julich; Eva-Carina Heier; Niklas Klein; Elmar Krause; Thomas Tschernig; Miroslaw Kornek; Frank Lammert; Detlef Schuppan; Veronika Lukacs-Kornek
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2015-11-12       Impact factor: 4.052
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