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Literature DB >> 19381353

Experimentally validated quantitative linear model for the device physics of elastomeric microfluidic valves.

Emil P Kartalov, Axel Scherer, Stephen R Quake, Clive R Taylor, W French Anderson.

Abstract

A systematic experimental study and theoretical modeling of the device physics of polydimethylsiloxane "pushdown" microfluidic valves are presented. The phase space is charted by 1587 dimension combinations and encompasses 45-295 μm lateral dimensions, 16-39 μm membrane thickness, and 1-28 psi closing pressure. Three linear models are developed and tested against the empirical data, and then combined into a fourth-power-polynomial superposition. The experimentally validated final model offers a useful quantitative prediction for a valve's properties as a function of its dimensions. Typical valves (80-150 μm width) are shown to behave like thin springs.

Entities: Chemical

Year: 2007 PMID： 19381353 PMCID： PMC2670093 DOI： 10.1063/1.2511688

Source DB: PubMed Journal: J Appl Phys ISSN： 0021-8979 Impact factor: 2.546

11 in total

Experimentally validated quantitative linear model for the device physics of elastomeric microfluidic valves.

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