Literature DB >> 19380646

Contained anastomotic leaks after colorectal surgery: are we too slow to act?

Scott M Damrauer1, Liliana Bordeianou, David Berger.   

Abstract

HYPOTHESIS: Contained and free anastomotic leaks, which occur in a small percentage of patients after colorectal surgery, are different clinical entities and consequently should be managed differently.
DESIGN: Retrospective medical record review.
SETTING: Academic medical center. PATIENTS: Patients who underwent colectomy with primary anastomosis (N = 4019) between January 1, 1992, and December 13, 2004, were eligible for participation in the study. Fifty-eight patients (1.5%) with an anastomotic leak demonstrated by communication between the collection and the gastrointestinal tract were identified. Twenty-eight of the patients had free leaks and 30 had contained leaks. MAIN OUTCOME MEASURES: Time to presentation, symptoms at presentation, rates of reexploration, and in-hospital mortality.
RESULTS: Baseline characteristics, presenting symptoms, physical examination findings, and laboratory values were similar between patients with contained and free leaks. Almost all patients with free leaks were taken directly to the operating room, whereas those with contained leaks were initially more likely to be treated nonoperatively. However, 24 of the 28 patients with contained leaks (86%) ultimately required surgical intervention. In-hospital mortality was the same in both groups (18% in the contained leak group and 17% in the free leak group).
CONCLUSIONS: In patients with contained leaks who have documented communication between the abscess cavity and the bowel, there is no difference in the rate of operative management or morbidity and mortality when compared with those with free leaks. This finding suggests that the categorization of leaks as free or contained may not be justified and argues for early operative intervention even in patients with contained leaks.

Entities:  

Mesh:

Year:  2009        PMID: 19380646     DOI: 10.1001/archsurg.2008.589

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  8 in total

1.  Endoscopic intraoperative anastomotic testing may avoid early gastrointestinal anastomotic complications. A prospective study.

Authors:  Eva Lieto; Michele Orditura; Paolo Castellano; Margherita Pinto; Anna Zamboli; Ferdinando De Vita; Carlo Pignatelli; Gennaro Galizia
Journal:  J Gastrointest Surg       Date:  2011-01       Impact factor: 3.452

Review 2.  Anastomotic Failure in Colorectal Surgery: Where Are We at?

Authors:  Vinna An; Raaj Chandra; Matthew Lawrence
Journal:  Indian J Surg       Date:  2018-03-03       Impact factor: 0.656

3.  Prognostic Factors and Significance of Gastrointestinal Leak After Cytoreductive Surgery (CRS) with Heated Intraperitoneal Chemotherapy (HIPEC).

Authors:  Konstantinos Chouliaras; Edward A Levine; Nora Fino; Perry Shen; Konstantinos I Votanopoulos
Journal:  Ann Surg Oncol       Date:  2016-12-19       Impact factor: 5.344

4.  Management and outcome of colorectal anastomotic leaks.

Authors:  Michael Thornton; Heman Joshi; Chandrakumar Vimalachandran; Richard Heath; Paul Carter; Ufuk Gur; Paul Rooney
Journal:  Int J Colorectal Dis       Date:  2010-11-25       Impact factor: 2.571

5.  Tailored treatment of anastomotic leak after rectal cancer surgery according to the presence of a diverting stoma.

Authors:  Chang Hyun Kim; Jaram Lee; Han Deok Kwak; Soo Young Lee; Jae Kyun Ju; Hyeong Rok Kim
Journal:  Ann Surg Treat Res       Date:  2020-08-27       Impact factor: 1.859

Review 6.  Endoscopic Full-Thickness Defects and Closure Techniques.

Authors:  Diogo T H de Moura; Amit H Sachdev; Christopher C Thompson
Journal:  Curr Treat Options Gastroenterol       Date:  2018-12

7.  Different clinical features according to the anastomotic leakage subtypes after rectal cancer surgeries: contained vs. free leakages.

Authors:  Eun Jung Park; Jeonghyun Kang; Hyuk Hur; Byung Soh Min; Seung Hyuk Baik; Kang Young Lee; Nam Kyu Kim
Journal:  PLoS One       Date:  2018-12-12       Impact factor: 3.240

8.  Thirty-seven patients treated with the C-seal: protection of stapled colorectal anastomoses with a biodegradable sheath.

Authors:  Annelien N Morks; Klaas Havenga; Henk O ten Cate Hoedemaker; Jeroen W A Leijtens; Rutger J Ploeg
Journal:  Int J Colorectal Dis       Date:  2013-06-14       Impact factor: 2.571

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.